pH-activatable oxidative stress amplifying dissolving microneedles for combined chemo-photodynamic therapy of melanoma

Huang, Yanjuan; Lai, Hanjiang; Jiang, Jingwen; Xu, Xiaoyu; Zeng, Zishan; Ren, Lingling; Liu, Qiuxing; Chen, Meixu; Zhang, Tao; Ding, Xin; Zhao, Chunshun; Cui, Shengmiao

doi:10.1016/j.ajps.2022.08.003

Cited by 26 publications

(8 citation statements)

References 56 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Simultaneous PTT for skin tumor [ 218] Microneedle patch PpIX-ADH-HA conjugated with PA-Fe 3+ complex Dihydroartemisinin DMNs, acidic pH triggered the degradation oxidation treatment Chemo-photodynamic therapy of melanoma [ 219] Microneedle patch HA derivatives Immunomodulatory nanoparticlecontaining drug, CpG oligodinucleotides Delivery of immune activators and collection of ISF to monitor therapeutic responses,…”

Section: Hama Melanin Nanoparticles Antioxidation and Photothermal Re...mentioning

confidence: 99%

Tailoring Hyaluronic Acid Hydrogels for Biomedical Applications

Luo,

Wang,

et al. 2023

Adv Funct Materials

View full text Add to dashboard Cite

Hyaluronic acid (HA) is an attractive anionic polysaccharide polymer with inherent pharmacological properties and versatile chemical groups for modification. Due to their water retention ability, biocompatibility, biodegradation, cluster of differentiation‐44 targeting, and highly designable capacity, HA hydrogels have been an emerging biomaterial, showing tailoring performance in terms of chemical modifications and hydrogel forms. Various preparation technologies have been developed for the fabrication of the tailoring HA hydrogels with unique structures and functions. They have been utilized in diverse biomedical applications like drug delivery and tissue engineering scaffolds. Herein, this review comprehensively summarizes the HA derivatives with different molecule weights and functional modifications. Then the various fabrication methods to obtain tailoring hydrogels in the forms of nanogel, nanofiber, microparticle, microneedle patch, injectable hydrogel, and scaffold are reviewed as well. The emphasis is focused on the shining biomedical applications of these tailoring HA hydrogels in anti‐bacteria, anti‐inflammation, wound healing, cancer treatment, regenerative medicine, psoriasis treatment, diagnosis, etc. The potentials and prospects are subsequently given to inspire further investigation, aiming at accelerating product translation from research to clinic.

show abstract

Section: Hama Melanin Nanoparticles Antioxidation and Photothermal Re...mentioning

confidence: 99%

Tailoring Hyaluronic Acid Hydrogels for Biomedical Applications

Luo,

Wang,

et al. 2023

Adv Funct Materials

View full text Add to dashboard Cite

show abstract

“…Photodynamic therapy has been exploited to combine with photothermal therapy, immunotherapy and chemotherapy to better suppress tumor progression [ [3] , [4] , [5] , [6] ]. A combination of chemotherapy and PDT has been reported to exhibit enhanced or synergistic therapeutic effect while reduce side effects and overcome the multidrug resistance of cytotoxic agents [ [7] , [8] , [9] , [10] , [11] , [12] , [13] , [14] ].…”

Section: Introductionmentioning

confidence: 99%

Reduction-responsive worm-like nanoparticles for synergistic cancer chemo-photodynamic therapy

et al. 2023

Materials Today Bio

View full text Add to dashboard Cite

“…29 Different types of MNs have slightly different uses. Among them, DMNs have attracted much attention because of their advantages such as simple production, low cost, biodegradability and biocompatibility, 30 as well as drug release control. 31,32 However, the stability, mechanical strength and drug loading capacity of DMNs are major problems.…”

Section: Introductionmentioning

confidence: 99%

Dissolving microneedles based on ZnO nanoparticles and an ionic liquid as synergistic antibacterial agents

et al. 2023

J. Mater. Chem. B

View full text Add to dashboard Cite

show abstract

pH-activatable oxidative stress amplifying dissolving microneedles for combined chemo-photodynamic therapy of melanoma

Cited by 26 publications

References 56 publications

Tailoring Hyaluronic Acid Hydrogels for Biomedical Applications

Tailoring Hyaluronic Acid Hydrogels for Biomedical Applications

Reduction-responsive worm-like nanoparticles for synergistic cancer chemo-photodynamic therapy

Dissolving microneedles based on ZnO nanoparticles and an ionic liquid as synergistic antibacterial agents

Contact Info

Product

Resources

About