pH-driven continuous stem cell production with enhanced regenerative capacity from polyamide/chitosan surfaces

Yen, Chia-Hsiang; Cheng, Nai‐Chen; Hsieh, Hao-Ying; Tsai, Ching-Wen; Lee, An‐Li; Lu, Chien-Yi; Chen, Yin-Tzu; Young, Tai‐Horng

doi:10.1016/j.mtbio.2022.100514

Cited by 2 publications

(1 citation statement)

References 64 publications

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“…Shrestha et al [ 176 ] reported that this type of scaffold could increase osteoblastic MC3T3-E1 cell growth, adhesion, differentiation and proliferation, to enhance osteogenic capabilities. Chia-Hsiang Yen et al [ 177 ] developed a platform for a continuous cell production, in which, by means of a change in the medium pH, adipose-derived stem cells were mass-produced with sustained regenerative capacity.…”

Section: Nylon As Materials For Biomedical Devicesmentioning

confidence: 99%

Nylons with Applications in Energy Generators, 3D Printing and Biomedicine

Arioli,

Puiggalí,

Franco

2024

Molecules

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Linear polyamides, known as nylons, are a class of synthetic polymers with a wide range of applications due to their outstanding properties, such as chemical and thermal resistance or mechanical strength. These polymers have been used in various fields: from common and domestic applications, such as socks and fishing nets, to industrial gears or water purification membranes. By their durability, flexibility and wear resistance, nylons are now being used in addictive manufacturing technology as a good material choice to produce sophisticated devices with precise and complex geometric shapes. Furthermore, the emergence of triboelectric nanogenerators and the development of biomaterials have highlighted the versatility and utility of these materials. Due to their ability to enhance triboelectric performance and the range of applications, nylons show a potential use as tribo-positive materials. Because of the easy control of their shape, they can be subsequently integrated into nanogenerators. The use of nylons has also extended into the field of biomaterials, where their biocompatibility, mechanical strength and versatility have paved the way for groundbreaking advances in medical devices as dental implants, catheters and non-absorbable surgical sutures. By means of 3D bioprinting, nylons have been used to develop scaffolds, joint implants and drug carriers with tailored properties for various biomedical applications. The present paper aims to collect evidence of these recently specific applications of nylons by reviewing the literature produced in recent decades, with a special focus on the newer technologies in the field of energy harvesting and biomedicine.

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Section: Nylon As Materials For Biomedical Devicesmentioning

confidence: 99%

Nylons with Applications in Energy Generators, 3D Printing and Biomedicine

Arioli,

Puiggalí,

Franco

2024

Molecules

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Stimuli-Responsive Substrates to Control the Immunomodulatory Potential of Stromal Cells

Castilla-Casadiego,

Loh,

Pineda-Hernandez

et al. 2024

Biomacromolecules

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Mesenchymal stromal cells (MSCs) have broad immunomodulatory properties that range from regulation, proliferation, differentiation, and immune cell activation to secreting bioactive molecules that inhibit inflammation and regulate immune response. These properties provide MSCs with high therapeutic potency that has been shown to be relevant to tissue engineering and regenerative medicine. Hence, researchers have explored diverse strategies to control the immunomodulatory potential of stromal cells using polymeric substrates or scaffolds. These substrates alter the immunomodulatory response of MSCs, especially through biophysical cues such as matrix mechanical properties. To leverage these cell−matrix interactions as a strategy for priming MSCs, emerging studies have explored the use of stimuli-responsive substrates to enhance the therapeutic value of stromal cells. This review highlights how stimuli-responsive materials, including chemo-responsive, microenvironment-responsive, magneto-responsive, mechano-responsive, and photoresponsive substrates, have specifically been used to promote the immunomodulatory potential of stromal cells by controlling their secretory activity.

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pH-driven continuous stem cell production with enhanced regenerative capacity from polyamide/chitosan surfaces

Cited by 2 publications

References 64 publications

Nylons with Applications in Energy Generators, 3D Printing and Biomedicine

Nylons with Applications in Energy Generators, 3D Printing and Biomedicine

Stimuli-Responsive Substrates to Control the Immunomodulatory Potential of Stromal Cells

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