pH-modulated ion-current rectification in a cysteine-functionalized glass nanopipette

Liu, Guochang; Gao, Meng-Juan; Chen, Wei; Hu, Xiaoyu; Song, Lai-Bo; Liu, Bo; Zhao, Yuan‐Di

doi:10.1016/j.elecom.2018.09.017

Cited by 23 publications

(13 citation statements)

References 47 publications

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“…At the pH value of 6.5, the value of r and zeta potential were −0.15 ± 0.11 and −7.87 ± 1.09 mV, respectively, indicating poor ICR in the neutral solution. It was fully demonstrated that pH controlled the direction and intensity of ICR by adjusting the surface charge of TDMP, which was consistent with our previous results in a hollow glass nanopipette. , …”

Section: Resultssupporting

confidence: 91%

Ion Current Rectification in High-Salt Environment from Mesoporous TiO₂ Microplug in Situ Grown at the Tip of a Micropipette Induced by Space-Confined Evaporation

et al. 2019

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In this work, in situ growth of a titanium dioxide microplug (TDMP) having mesoporous channels at the tip of a glass micropipette induced by space-confined evaporation is reported. Moreover, clear ion current rectification (ICR) of a single-material nanopore in a saturated potassium chloride solution is observed for the first time. TDMP presents an asymmetrical channel structure with the top and bottom apertures of 12.3 ± 6.1 and 42.6 ± 19.7 nm, respectively. TDMP exhibits outstanding ICR capability as the ions get transported through it due to the applied potential. The values for the rectification coefficient (r = log2|I +1 V/I –1 V|) in a saturated KCl solution under acidic (pH of 3.0) and alkaline (pH of 10.0) environments are 1.32 and −0.84, respectively. The intensity and direction of ICR can be adjusted by pH or through the modification of citric acid. Meanwhile, the length and ion transport behavior of TDMP under different growth conditions (time and diameter) were also investigated. TDMP with asymmetric mesoporous channels, maintaining ICR in a saturated salt solution, is expected to expand the application of nanopores in high-salt environments. Furthermore, growth of mesoporous material in the micropipette facilitates the miniaturization of the nanopore device, which further promotes its application potential.

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Section: Resultssupporting

confidence: 91%

Ion Current Rectification in High-Salt Environment from Mesoporous TiO₂ Microplug in Situ Grown at the Tip of a Micropipette Induced by Space-Confined Evaporation

et al. 2019

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“…286 In the absence of polymerization, silanization forms thin coatings with low surface density, which may be used to increase hydrophobicity 185,190 or to reduce non-specific surface adhesion. 283 In the context of nanopores, silanization allows for the functionalization of pore walls by enabling the attachment of DNA, 173,175,178,183 dendrimers, 174 nucleoporins, 176 aldehydes, 172,177 spiropyran moieties, 181 cysteines, 187 carboxylic acid, 172 EDTA, 188 peptides, 189,191 and polymer brushes 182 to chemical groups that are attached to the silane molecule. Apart from the possibility of such attachments, silanization can generate a coating with antifouling properties 184 and can be used to manipulate ICR 185 and other charge-based properties, 179 including the modulation of surface charge by changing the pH value of the recording electrolyte 129,180,186 Fig .…”

Section: Nanopore Coatings By Silanizationmentioning

confidence: 99%

Surface coatings for solid-state nanopores

2019

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“…A macroscopic concept of the rectification is composed of (i) geometric obstacle of the ion transport through the hole in the closed state and (ii) the localized accumulation of electrolyte owing to ion-exchange membrane in the open state [19,29,30]. A concept from the microscopic viewpoints is a gate linked to the potential distribution in the double-layer or on pore walls [31][32][33][34][35][36][37] as well as molecular instability in a hydrodynamic vortex [38,39].…”

Section: Introductionmentioning

confidence: 99%

Electric Migration of Hydrogen Ion in Pore-Voltammetry Suppressed by Nafion Film

Liu

Aoki²,

Chen

2020

Electrochem

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Micro-hole voltammetry exhibiting rectified current-voltage curves was performed in hydrochloric acid by varying the lengths and the diameters of the micro-holes on one end of which a Nafion film was mounted. Some voltammetric properties were compared with those in NaCl solution. The voltammograms were composed of two line-segments, the slope of one segment being larger than the other. They were controlled by electric migration partly because of the linearity of the voltammograms and partly the independence of the scan rates. Since the low conductance which appeared in the current from the hole to the Nafion film was proportional to the cross section area of the hole and the inverse of the length of the hole, it should be controlled by the geometry of the hole. The conductance of the hydrogen ion in the Nafion film was observed to be smaller than that in the bulk, because the transport rate of hydrogen ion by the Grotthuss mechanism was hindered by the destruction of hydrogen bonds in the film. In contrast, the conductance for the current from the Nafion to the hole, enhancing by up to 30 times in magnitude from the opposite current, was controlled by the cell geometry rather than the hole geometry except for very small holes. A reason for the enhancement is a supply of hydrogen ions from the Nafion to increase the concentration in the hole. The concentration of the hydrogen ion was five times smaller than that of sodium ion because of the blocking of transport of the hydrogen ion in the Nafion film. However, the rectification ratio of H+ was twice as large as that of Na+.

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pH-modulated ion-current rectification in a cysteine-functionalized glass nanopipette

Cited by 23 publications

References 47 publications

Ion Current Rectification in High-Salt Environment from Mesoporous TiO₂ Microplug in Situ Grown at the Tip of a Micropipette Induced by Space-Confined Evaporation

Ion Current Rectification in High-Salt Environment from Mesoporous TiO₂ Microplug in Situ Grown at the Tip of a Micropipette Induced by Space-Confined Evaporation

Surface coatings for solid-state nanopores

Electric Migration of Hydrogen Ion in Pore-Voltammetry Suppressed by Nafion Film

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pH-modulated ion-current rectification in a cysteine-functionalized glass nanopipette

Cited by 23 publications

References 47 publications

Ion Current Rectification in High-Salt Environment from Mesoporous TiO2 Microplug in Situ Grown at the Tip of a Micropipette Induced by Space-Confined Evaporation

Ion Current Rectification in High-Salt Environment from Mesoporous TiO2 Microplug in Situ Grown at the Tip of a Micropipette Induced by Space-Confined Evaporation

Surface coatings for solid-state nanopores

Electric Migration of Hydrogen Ion in Pore-Voltammetry Suppressed by Nafion Film

Contact Info

Product

Resources

About

Ion Current Rectification in High-Salt Environment from Mesoporous TiO₂ Microplug in Situ Grown at the Tip of a Micropipette Induced by Space-Confined Evaporation

Ion Current Rectification in High-Salt Environment from Mesoporous TiO₂ Microplug in Situ Grown at the Tip of a Micropipette Induced by Space-Confined Evaporation