pH-responsive aggregates consisted of oligodeoxynucleotides bearing nitrophenol group that deliver drugs into acidic cells

Yokota, Shohei; Motohashi, Yuto; Nishihara, Tatsuya; Tanabe, Kazuhito

doi:10.1016/j.bmcl.2021.128519

Cited by 1 publication

(1 citation statement)

References 18 publications

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“…The reduction of 4-NPh, performed in the presence of NaBH 4 at room temperature and using the catalysts listed above, is expected to take place in two steps [51]. Firstly, the 4-NPh is spontaneously converted to p-nitrophenolate ion (4-NPh -) by the addition of NaBH 4 (pH reaction medium ~11, pK a(4-NPh) = 7.1) [52], which changes the color of the solution from pale to deep yellow. In the second step, in the presence of catalysts, the hydrogenation of 4-NPh − takes place to form a colorless solution of 4-APh.…”

Section: Catalytic Performancementioning

confidence: 99%

Highly Efficient and Magnetically Recyclable Non-Noble Metal Fly Ash-Based Catalysts for 4-Nitrophenol Reduction

Kuźniarska-Biernacka,

Ferreira,

Monteiro

et al. 2023

Catalysts

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4-nitrophenol (4-NPh) is a harmful compound produced in large amounts in the chemical industry, and its reduction to aminophenol (4-APh) using noble metals as catalysts is one of the most studied processes. The development of noble metal-free catalysts represents an economic advantage in large-scale applications and contributes to the sustainability of raw materials. Coal fly ash (FA), a major waste stream from coal combustion, contains an easily recoverable magnetic fraction (FAmag sample) composed of Fe-rich particles that could substitute noble metal catalysts in 4-NPh reduction, with the concomitant advantage of being easily recovered via magnetic separation. For this purpose, a new composite material containing copper ferrite nanoparticles (FAmag@CS@CuFe) was prepared via a facile, environmentally friendly and cost-effective method based on three components: FAmag as the core, a biobased polymer chitosan (CS) as the linker and copper ferrite CuFe2O4 nanoparticles (CuFe) as the active sites. The structure, morphology, composition and magnetic properties of the FAmag@CS@CuFe material were studied to assess the efficiency of the preparation. It was found that the biopolymer prevented the aggregation of CuFe nanoparticles and enabled a synergistically outstanding activity towards the reduction of 4-NPh in comparison to the pristine FAmag and bare CuFe nanoparticles. The FAmag@CS@CuFe catalyst showed efficiency and stability in the conversion of 4-NPh of up to 95% in 3 min over four consecutive cycles. Such remarkable catalytic results demonstrate the potential of this catalyst as a substitute for expensive noble metals.

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Section: Catalytic Performancementioning

confidence: 99%