pH-responsive glycodendrimer as a new active targeting agent for doxorubicin delivery

Lignocellulosic–biomolecules conjugated systems: green-engineered complexes modified by covalent linkers

“…Thus, CCA-ATPES-GLA-RSV is an excellent example of a successful multi-building system under alkali conditions for improved osteointegration. [104][105][106][107] Moreover, ATPES can be an initial linker for cellulose nanocrystals to construct poly(propylene imine)-cellulose dendrimers conjugate for profile release study of doxorubicin (DOX) -an anticancer drug. 108 Authors also use the union of linkers' fragments to maximize the binding among cellulose feedstock and biomolecules.…”

“…112,129 Moreover, lignocellulosic conjugates showed the use of hazardous linkers, such as chloroacetyl chloride -a greener alternative such as diethylamine is recommended, even though they are less effective. 104,130 Moreover, toxic solvents such as toluene, pyridine, and DMF can be replaceable for benzene, triethylamine, and acetonitrile. 10,131 Alternatively, other solvents, such as deep eutectic 132 or ''greener'' solvent candidates (e.g., glycerolderived 1,2,3-triethoxypropane) 133 can be explored.…”

A Recent Review on Cancer Nanomedicine

“…A dendrimer can be built on virtually any form of chemistry, and the nature of that chemistry greatly influences its solubility, degradability, and biological activity [ 159 ]. Polyamidoamines (PAMAM) [ 160 ], poly- l -lysine (PLL) [ 161 ], polyamides (polypeptides) [ 162 ], poly (propylene imine) [ 163 ], and carbohydrates [ 164 ] are some of the most frequently used forms of dendrimers in biological applications. However, PAMAM dendrimers are the most prevalent dendrimer scaffold, commercially available with a wide range of generations and surface properties.…”