Phaeohyphomycosis Due to <i>Exophiala oligosperma</i> in an Immunocompromised Host

Nishikawa, Hirofumi; Taniguchi, Yoshinori

doi:10.3899/jrheum.180774

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2020

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“…More than a hundred species and sixty genera of these fungi are connected to a broad spectrum of human infections [1]. The main clinical forms of presentation of the infections through these dematiaceous fungi include phaeohyphomycoses (cutaneous, subcutaneous and systemic), that affect both immunocompetent and immunocompromised individuals [2].…”

Section: Introductionmentioning

confidence: 99%

Cutaneous phaeohyphomycosis caused by Exophiala xenobiotica: A case report

Espanhol

Recuero

Pagani

et al. 2020

Medical Mycology Case Reports

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We report a case of phaeohyphomycosis that affected the leg of a 45-year-old Brazilian man, car mechanic and renal transplanted. The direct mycological examination evidenced dematiaceous septated hyphae. The pathogenic fungal species was identified as Exophiala xenobiotica. Antifungal activity in vitro revealed terbinafine as the best antifungal. For treatment, it was chosen surgical excision of the entire lesion and used systemic itraconazole. Phaeohyphomycosis caused by Exophiala xenobiotica is extremely rare and is closely related to transplant patients.

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Section: Introductionmentioning

confidence: 99%