2004
DOI: 10.1007/s10517-005-0098-4
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Phagocytic activity of neutrophils and lymphocytes at various periods of storage in the state of cold anabiosis (-40°C)

Abstract: We studied changes in phagocytic activity of neutrophils and lymphocytes subjected to cold anabiosis. The proposed effective method for introduction of human blood leukocytes into cold anabiosis at moderately low temperature (-40 o C) in the presence of a cryopreserving agent does not require washout of the biological material after defrosting.

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“…1). Thus, although there have been some papers that have reported the phagocytic activity of lymphocytes (Koszewski et al 1957;Svedentsov et al 2004), our data is consistent with the present consensus (Brown 1991;Lee et al 2003;Underhill and Ozinsky 2002) that monocytes and neutrophils, but not lymphocytes, play central roles in the elimination of bacterial pathogens in vivo.…”
Section: Discussionsupporting
confidence: 92%
“…1). Thus, although there have been some papers that have reported the phagocytic activity of lymphocytes (Koszewski et al 1957;Svedentsov et al 2004), our data is consistent with the present consensus (Brown 1991;Lee et al 2003;Underhill and Ozinsky 2002) that monocytes and neutrophils, but not lymphocytes, play central roles in the elimination of bacterial pathogens in vivo.…”
Section: Discussionsupporting
confidence: 92%