Phagocytic efficiency and cytotoxic responses of Indian freshwater sponge (Eunapius carteri) cells isolated by density gradient centrifugation and flow cytometry: a morphofunctional analysis

Mukherjee, Soumalya; Ray, Mitali; Ray, Sajal

doi:10.1016/j.zool.2014.07.002

Cited by 24 publications

(20 citation statements)

References 49 publications

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“…Primitive multicellular organisms such as sponges, which evolved over 500 000 000 years ago, contain a heterogeneous population of pluripotent mesenchymal ameboid cells (archeocytes) that are phagocytic and function as stem cells. In addition to nutrient uptake, distribution, and storage, they also provide a means of organismal defense [26]. Even phagocytic cells must be mobilized, however, which requires intercellular communication, and the use of secreted, diffusible signals is phylogenetically older than neurotransmission.…”

Section: Evolution Of Neuroimmune Integrationmentioning

confidence: 99%

Cellular Organization of Neuroimmune Interactions in the Gastrointestinal Tract

Margolis

Gershon

Bogunovic

2016

Trends in Immunology

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The gastrointestinal (GI) tract is the largest immune organ; in vertebrates, it is the only organ whose function is controlled by its own intrinsic enteric nervous system (ENS), but it is additionally regulated by extrinsic (sympathetic and parasympathetic) innervation. The GI nervous and immune systems are highly integrated in their common goal, which is to unite digestive functions with protection from ingested environmental threats. This review discusses the physiological relevance of enteric neuroimmune integration by summarizing the current knowledge of evolutionary and developmental pathways, cellular organization, and molecular mechanisms of neuroimmune interactions in health and disease.

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Section: Evolution Of Neuroimmune Integrationmentioning

confidence: 99%

Cellular Organization of Neuroimmune Interactions in the Gastrointestinal Tract

Margolis

Gershon

Bogunovic

2016

Trends in Immunology

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“…Hemocytes of aquatic mollusks upon treatment with xenobiotics yield multiple morphological aberrations like vacuolation, membrane disintegration, cellular disruption, and shift in size and shape [2]. (Figure 4) is established as an innate immunological response reported in all major invertebrate Phyla [8,9]. It is characterized by sequential-like recognition, chemotaxis, contact, and internalization followed by the degradation of the target in the cell's interior.…”

Section: Morphological Aberrations Of Invertebrate Blood Cells As a Mmentioning

confidence: 99%

Levels of Toxicity Screening of Environmental Chemicals Using Aquatic Invertebrates - A Review

Ray¹

2016

Invertebrates - Experimental Models in Toxicity Screening

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Effective screening of the toxicity of chemicals using living organisms has been considered as a major issue of environmental biomonitoring. The principle of toxicity screening involves the quantitation of toxin-induced shift of biological response or tissue morphology of test species both in vivo and in vitro. Most of the toxin appears to function as biological response modifiers at a defined concentration and span of exposure. In recent years, invertebrates have been gaining a special scientific attention for being utilized as suitable model for toxicity screening. Invertebrates like crab, mollusks, sponge, and earthworm have already been established as model organisms for toxicity screening and analyses. " number of environmental toxins like arsenic, pyrethroid, pesticides, heavy metals, and washing soda can be screened for their toxicities using invertebrate species. Cellular and subcellular parameters like blood cell density, lysosomal membrane stability, cellular damage, apoptosis, micronucleation, and cytotoxic response of invertebrates had been established as biomarkers of environmental toxicity. Toxin-induced histopathological and behavioral shift had been suggested as effective parameters of toxicity screening in model invertebrates. However, reactivity and responses of invertebrates toward xenobiotics are often recorded to be species specific and related to the chemistry of the toxin. Current article reviews different levels of toxicity screening using invertebrate as test model.

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“…The extent of damage was photographed the next morning (Image 4C-F). Pieces of body mass with an approximate dimension of 0.5 cm 3 were excised with a scalpel and examined for viability of sponge specimens by smearing the trace amount of cells over glass slides and stained with 0.4% trypan blue following the principle of dye exclusion (Mussino et al 2013;Mukherjee et al 2015a). …”

Section: Documentation Of the Freshwater Sponges Before And After Thementioning

confidence: 99%

A report of hailstorm damage to two species of freshwater sponge (Demospongiae: Haplosclerida: Spongillidae) populations of West Bengal, India

Mukherjee

Ray

2016

J. Threat. Taxa

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Phagocytic efficiency and cytotoxic responses of Indian freshwater sponge (Eunapius carteri) cells isolated by density gradient centrifugation and flow cytometry: a morphofunctional analysis

Cited by 24 publications

References 49 publications

Cellular Organization of Neuroimmune Interactions in the Gastrointestinal Tract

Cellular Organization of Neuroimmune Interactions in the Gastrointestinal Tract

Levels of Toxicity Screening of Environmental Chemicals Using Aquatic Invertebrates - A Review

A report of hailstorm damage to two species of freshwater sponge (Demospongiae: Haplosclerida: Spongillidae) populations of West Bengal, India

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