The international generalisability of evidence for health policy: a cross country comparison of medication adherence following policy change.Health Policy http://dx.doi.org/10. 1016/j.healthpol.2016.10.009 This is a PDF Þle of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its Þnal form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
1
Title Page TitleThe international generalisability of evidence for health policy: a cross country comparison of medication adherence following policy change
Running title
Conflicts of InterestSJS and HW have no conflicts of interest. At the time that the study was carried out, JMP received salary support from CVS Caremark for unrelated research on medication adherence. JMF received salary support from CVS Caremark and Merck for unrelated research on medication adherence.
2
KeywordsPharmaceutical policy, Cost sharing, Medication adherence, Generalisability
Word count
~3,2003 Highlights We addressed the question of how generalisable evidence for policy making is across health systems by using a case study of two similar copayment policies in two different health systems and assessing the impact of each policy on adherence. Two similar copayment policies, in apparently similar health systems, did not invoke similar responses in adherence to medications. Nuanced differences between the health systems and the patients within them may affect differences in impact of policies. Before applying evidence from one health system to the another health system, critical questions of the local applicability of the evidence are key to maximising its' utility.
4
AbstractIntroduction of copayments for prescriptions may increase morbidity and mortality.