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“…Applications of fluorescence methods in phar maceutical analysis have been discussed by several authors (83,195,493). A general method for detecting or determining amino or heterocyclic nitrogen is based on a reaction with a fluorescein to yield a more intensely fluorescent rhodamine dye (494)-for example, atropine can be determined with high sensitivity by condensation with eosin in chloroform solution and measuring the 580-mg fluorescence produced (278).…”
Section: Drugsmentioning
confidence: 99%
“…Applications of fluorescence methods in phar maceutical analysis have been discussed by several authors (83,195,493). A general method for detecting or determining amino or heterocyclic nitrogen is based on a reaction with a fluorescein to yield a more intensely fluorescent rhodamine dye (494)-for example, atropine can be determined with high sensitivity by condensation with eosin in chloroform solution and measuring the 580-mg fluorescence produced (278).…”
Section: Drugsmentioning
confidence: 99%
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