2016
DOI: 10.7897/2230-8407.07324
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Pharmacodynamic Interaction of Quercetin and Silymarin Against Cyclophosphamide Induced Cardio-Toxicity

Abstract: The study was designed to investigate the cardioprotective effect of different combination of Silymarin and Quercetin against Cyclophosphamide induced cardiotoxicity in experimental rats. The Albino rats of either sex were divided into five groups of six animals. Group 1 and group 2 served as normal and control group respectively. Other groups treated with Silymarin (60 mg/kg, p.o.) alone, high (30 mg/kg, p.o.) and low (15 mg/kg, p.o.) dose of Silymarin combined with Quercetin (10 mg/kg, p.o.). Myocardial dama… Show more

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