2014
DOI: 10.1097/fpc.0000000000000054
|View full text |Cite
|
Sign up to set email alerts
|

Pharmacogenomic characterization of gemcitabine response – a framework for data integration to enable personalized medicine

Abstract: Objectives Response to the oncology drug gemcitabine may be variable in part due to genetic differences in the enzymes and transporters responsible for its metabolism and disposition. The aim of our in-silico study was to identify gene variants significantly associated with gemcitabine response that may help to personalize treatment in the clinic.Methods We analyzed two independent data sets: (a) genotype data from NCI-60 cell lines using the Affymetrix DMET 1.0 platform combined with gemcitabine cytotoxicity … Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

0
0
0

Publication Types

Select...

Relationship

0
0

Authors

Journals

citations
Cited by 0 publications
references
References 59 publications
0
0
0
Order By: Relevance

No citations

Set email alert for when this publication receives citations?