Pharmacognostic evaluation of the leaves and roots of Cassia sieberiana DC.

Omolola, T Fatokun; Esievo, Kevwe Benefit; Jemilat, A Ibrahim; Oluyemisi, F Kunle

doi:10.5897/jpp2017.0461

Cited by 6 publications

(5 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This variation can also be due to duration of the extraction and part of the plant used. The trend observed from the result of this study is in agreement with Fatokun et al (2017).…”

Section: Discussionsupporting

confidence: 91%

“…This variation may be attributed to the difference in the parts of the plant used for the investigation. Although the result abtained from this study agrees with result of Fatokun et al (2017) who reported acid insoluble ash of 1.5 % (w/w) from the root bark of the plant.…”

Section: Discussionsupporting

confidence: 89%

“…The ash value indicates the presence of inorganic salts occurring naturally in the crude drug or adhering to it or those deliberately added to it as adulterant (WHO, 2011). The total ash (Table III) obtained from this study was found to lower than that reported by Sam et al (2011);Fatokun et al (2017) who recorded 7.90 % (w/w) and 7.4 % (w/w) respectively from the root bark of C. sieberiana. This deviation may be due to the difference in the parts of the plant used for the study.…”

Section: Discussioncontrasting

confidence: 86%

“…The presence of excessive moisture encourages bacterial, fungal or yeast growths and deterioration of the active constituents following hydrolysis (WHO, 2011). The percentage moisture (Table III) was higher than that reported by Fatokun et al (2017) who indicated moisture content of 4.5 % (w/w) from root bark of C. sieberiana. The difference may be due to storage environment.…”

Section: Discussioncontrasting

confidence: 66%

See 3 more Smart Citations

Phytochemical and antioxidant evaluation of cassia sieberiana D.C. stem bark extracts

Mshelia

Mathias

Umaru

et al. 2020

PNgAS

View full text Add to dashboard Cite

Cassia sieberiana D.C. belongs to the Fabaceae family and it is used ethnomedically in the management of cancer, diabetes and other diseases. There is a growing concern about the scourge of diseases caused by excessive free radicals in the body and lack of standardization of medicinal herbal products. Therefore, this research is aimed at evaluating the phytochemical and free radical scavenging activities of the plant extracts with the view to identify the chemical constituents and antioxidant properties of the extracts. The powdered stem bark was evaluated for its pharmacognostic profiles and then extracted successively with the aid of Soxhlet extractor using n-hexane, ethyl acetate and methanol. The extracts obtained were concentrated using rotary evaporator and the percentage yields of the extracts were determined. The extracts were screened for their phytochemical constituents using standard protocols. The thin layer chromatography (TLC) profiles of the resulting extracts were determined using suitable solvent systems and the retention factor (Rf) values of separated spots of compounds were calculated. The total phenolic content of the ethyl acetate and methanol extracts were measured using Folin-Ciocalteu reagent and gallic acid was used as standard. The antioxidant (free radical scavenging) activity of the extracts were measured using DPPH (2, 2-diphenyl-1- picryl hydrazyl) and ascorbic acid was used as standard. The results were expressed in terms of percentage inhibition. The percentage yields of the extracts were: 0.52 %, 6.58 % and 10.52 % respectively for n-hexane, ethyl acetate and methanol. The preliminary phytochemical screening of the extracts revealed the presence of tannins, cardiac glycosides, saponins, flavonoids and triterpenoid/steroids. Also, the total phenolic contents were found to 7.64 mg and 2.97 mg gallic acid equivalents for ethyl acetate and methanolic extract respectively. The free radical scavenging activity of the extracts revealed higher activity in the ethyl acetate extract. The results indicated that the extracts contain phenolic compounds which may be responsible for the antioxidant activity.

show abstract

“…This variation can also be due to duration of the extraction and part of the plant used. The trend observed from the result of this study is in agreement with Fatokun et al (2017).…”

Section: Discussionsupporting

confidence: 91%

Section: Discussionsupporting

confidence: 89%

Section: Discussioncontrasting

confidence: 86%

Section: Discussioncontrasting

confidence: 66%

See 2 more Smart Citations

Phytochemical and antioxidant evaluation of cassia sieberiana D.C. stem bark extracts

Mshelia

Mathias

Umaru

et al. 2020

PNgAS

View full text Add to dashboard Cite

show abstract

“…The moisture content of U. chamae (7.59 ± 1.24) is indicative of low moisture content. This is slightly below limit for water content (8 to 14%) for vegetable drugs (African Pharmacopoeia, 1985;Fatokun et al, 2017). Extractive values are used to determine the number of active constituents in a defined amount of plant material when extracted with a particular solvent.…”

Section: -246mentioning

confidence: 99%

Pharmacognostic standards for Uvaria chamae P. Beauv. leaves (Annonaceae)

Obia¹,

Sonibare²,

Adebodunb³

2023

njpr

View full text Add to dashboard Cite

Background : Standardisation as a tool in quality control ensures purity, safety and efficacy of herbal medicines. Uvaria chamae from the family Annonaceae has wide medicinal application which includes its use as a febrifuge and as an anti-inflammatory.Objective: The study was aimed at developing some Pharmacognostic standards for the leaves of U. chamae.Material and Methods: Uvaria chamae plant was collected, identified and authenticated. Fresh leaves were examined macroscopically and microscopically based on standard procedures. Fluorescence behavior was assessed by adding various reagents and viewing at daylight, 254 nm and 365 nm. Chemomicroscopy and physicochemical analysis of powdered samples were done using standard procedures. Phytochemical and Thin layer chromatographic analysis of the extracts were also carried out.Results: Leaves of U. chamae are alternately arranged and elliptic in shape. The abaxial surface has straight polygonal epidermal cells with paracytic stomata. Vascular bundles are arranged in fan shape from the transverse section of the leaf. Chemomicroscopic evaluation revealed the presence of lignin, starch and oil. Alcohol and water soluble extractive values were 4.00 ± 0.00 and 5.6 ± 0.67, respectively. The membrane stabilization activity of the extracts at 0-1 mg exceeded that of the standard drug diclofenac. The ethyl acetate fraction had the highest percentage of inhibition of haemolysis at 0.4 mg.Conclusion: The features established in this study may contribute in the identification and quality control of U. chamae.

show abstract