Pharmacognostical and phytochemical studies of Mollugo nudicaulis Lam.: A controversial plant origin ayurvedic drug

Pratap, Goli Penchala; Jyothi, B.; Husain, Mohd Kashif; Nagaraj, Vallepu; Sudarsanam, G.

doi:10.21276/ap.2021.10.2.5

Cited by 3 publications

(12 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The organoleptic properties were observed and noted as per standard procedures. [18][19][20][21][22]…”

Section: Macroscopic and Organoleptic Evaluationmentioning

confidence: 99%

“…The root powder was subjected to powder microscopy and maceration studies using the standard procedures. [18][19][20][21][22]…”

Section: Microscopic Evaluationmentioning

confidence: 99%

“…Physicochemical standards like pH of the water extract of root powder, ash, extractive and limit tests for heavy metals values were accomplished as per the standard procedures. [14][15][16][17][18][19][20][21][22]…”

Section: Determination Of Physicochemical Parametersmentioning

confidence: 99%

“…The pharmacognostic standardization of crude drugs is the only source to stop adulteration and ensure the end products therapeutic efficacy without adulteration. [17][18][19][20][21][22] The present study aims to standardize the Balamulachurna with the use of pharmacognostic tools.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Pharmacognostical Standardization of Balamulachurna- Root Powder of Sida rhombifolia subsp. retusa (L.) Borssum

Kumari¹,

Prasad²,

Pratap³

et al. 2022

Pharmacogn. Res.

View full text Add to dashboard Cite

Background: Ksheerabala tailam is well known Ayurvedic herbal formulation which is used in inflammations, pains and neurological disorders. The primary botanical source for Ksheerabala tailam is Balamulachurna. The literature refers to Balamulachurna as either of the root powders of Sida cordifolia, Sida acuta, Sida cordata or Sida rhombifolia subsp. retusa. To accomplish the clinical efficacy of Ksheerabala tailam, standardization of Balamulachurna is necessary. Objectives:The study is aimed to establish pharmacognostic standards of Balamulachurna with respect to Sida rhombifolia subsp. retusa root powder. Materials and Methods: Pharmacognostical standardization was carried out by focusing on organoleptic, macroscopic, microscopic, preliminary phytochemical evaluation, heavy metal assessments, fluorescence and HPTLC studies. Results: The roots macroscopic features were noticed as; an elongated taproot with few lateral roots, thick, woody, brown-coloured and bitter to taste. Organoleptic characteristics revealed the nature of the root powder as cream in colour with a pleasant odour and slightly bitter taste. The powder microscopic study specified the presence of fibres, fibre-sclereids, tracheids, vessel elements and calcium oxalate crystals. Physicochemical studies assessed total ash (7.5%), water-soluble ash (4.46%), alkalinity of water-soluble ash (0.4 ml) and acid-insoluble ash (3.3%). The preliminary phytochemical analyses revealed the presence of glycosides, alkaloids, phenols, flavonoids, tannins, terpenoids, and quinones. The HPTLC analyses exhibited various R f values with the diversity of multiple phytoconstituents. Conclusion: The scientific data generated by the study is beneficial for adequately identifying and establishing standards for using Sida rhombifolia subsp. retusa as a primary drug for maintaining the quality and purity of the Ksheerabala tailam, an Ayurvedic formulation.

show abstract

“…The organoleptic properties were observed and noted as per standard procedures. [18][19][20][21][22]…”

Section: Macroscopic and Organoleptic Evaluationmentioning

confidence: 99%

“…The root powder was subjected to powder microscopy and maceration studies using the standard procedures. [18][19][20][21][22]…”

Section: Microscopic Evaluationmentioning

confidence: 99%

Section: Determination Of Physicochemical Parametersmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Pharmacognostical Standardization of Balamulachurna- Root Powder of Sida rhombifolia subsp. retusa (L.) Borssum

Kumari¹,

Prasad²,

Pratap³

et al. 2022

Pharmacogn. Res.

View full text Add to dashboard Cite

show abstract

“…It is present in India, particularly in southern and eastern regions [14]. Plants of the Molluginaceae family have been reported for multiple medicinal benefits [15]. The plant has a great potential to deliver therapeutic effects such as antioxidants which could control the cell damaging free radicals [16], anthelmintic which can kill different worms, hepatoprotective which can cure and manage liver-related diseases [17], analgesic which can control pain, anti-inflammatory which can control different inflammatory disorders [18], and anti-hyperglycemic which can help in diabetic management [19].…”

Section: Introductionmentioning

confidence: 99%

In vitro evaluation of the antibacterial potential of flavonoid glycosides from Glinus oppositifolius (L.) Aug. DC.

Kannan¹,

Kandavel²,

Rajalakshmi³

et al. 2022

J App Biol biotech

View full text Add to dashboard Cite

Infectious diseases caused by microorganisms are one of the major causes of morbidity and mortality around the world. Emergence of new infectious strains and evolution of antibiotic resistance among them are the major threats the man kind is facing. This expands the need of discovery of newer and stronger antimicrobial compounds from the safer sources such as plants. Glinus oppositifolius (L.) Aug. DC. is a perennial herb which is predominantly being used in traditional medicine across different ethnicity. The plant extract has been reported to contain several medicinally important secondary metabolites; however, research on purified compounds from the plant is highly limited. This present study is focused to extract and partially purify flavonoid glycosides from G. oppositifolius and to evaluate its antibacterial efficiency. The aerial parts of G. oppositifolius were macerated and extracted and tested for presence of flavonoid glycosides which are potent anti-bacterial compounds. The quantitative estimation has shown 210.83 ± 4.63 mg of flavonoids and 167.77 ± 1.73 mg of carbohydrates per gram of dry extract. Further, partially purified flavonoid glycosides were isolated from the crude extract using silica gel column chromatography and quantitatively tested to contain 67.92 ± 0.58 mg of flavonoids and 38.54 ± 1.75 mg of carbohydrates per gram of dry fraction. The partially purified fractions were subjected to high-performance liquid chromatographic separation for further purification. In vitro antibacterial activity and minimum inhibitory concentration of the flavonoid glycosides were examined against six pathogenic bacteria through well diffusion and micro dilution methodologies. The flavonoid glycosides showed strong antibacterial activity against all bacteria tested. The concentration of 2800 μg/ml has registered 100% of inhibition against all bacteria tested. Conclusively, the results from the present study indicated that the methanolic extract of G. oppositifolius can yield good amount of flavonoid glycoside which shows strong and significant antibacterial activity and can be further explored for different medical applications.

show abstract

Phyto-Pharmacognostical Standardization of Three Morpho-Variants of Cissus quadrangularis L.

Pratap,

Husain,

Prasad

et al. 2024

Pharmacogn. Res.

View full text Add to dashboard Cite

Pharmacognostical and phytochemical studies of Mollugo nudicaulis Lam.: A controversial plant origin ayurvedic drug

Cited by 3 publications

References 0 publications

Pharmacognostical Standardization of Balamulachurna- Root Powder of Sida rhombifolia subsp. retusa (L.) Borssum

Pharmacognostical Standardization of Balamulachurna- Root Powder of Sida rhombifolia subsp. retusa (L.) Borssum

In vitro evaluation of the antibacterial potential of flavonoid glycosides from Glinus oppositifolius (L.) Aug. DC.

Phyto-Pharmacognostical Standardization of Three Morpho-Variants of Cissus quadrangularis L.

Contact Info

Product

Resources

About