Pharmacognostical Evaluation of Different Parts of Coleus amboinicus lour., Lamiaceae

Hullatti, Kirankumar; Bhattacharjee, Prasenjit

doi:10.5530/pj.2011.24.8

Cited by 13 publications

(9 citation statements)

References 6 publications

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“…17 In the latter study, there was no increase in mammary cell number. Despite the use of torbangun in many medical conditions such as malarial fever, hepatopathy, renal calculi, and chronic asthma, 18 little is known about its specific properties. Phytochemical screening of the plant reveals the presence of alkaloids, flavonoids, tannins, and saponins in its extracts.…”

Section: Resultsmentioning

confidence: 99%

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Systematic Review of the Efficacy of Herbal Galactogogues

2013

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Exclusive breastfeeding has been linked to many positive health outcomes, yet its widespread adoption as the primary mode of providing nutrition to infants remains challenging. The most common reported reason for early breastfeeding cessation is perception of inadequate milk production. To augment breast milk production, a substantial number of women turn to herbal galactogogues despite the limited scientific evidence of their efficacy and safety. We conducted a systematic review of published literature to evaluate the efficacy of herbal galactogogues. PubMed was searched from inception to October 2012 using an iterative search process that proceeded from broad categories to specific herbs. Manuscript references were also reviewed. Only experimental studies with objective outcome measures were included. Six trials met our search criteria. Using an adapted version of the CONSORT checklist, each trial was evaluated for potential sources of bias in design and reporting. Shatavari, torbangun, fenugreek, milk thistle, and a Japanese herbal medication were the 5 herbal preparations studied. Five trials found an increase in breast milk production. Several limitations exist that affect the validity of the trial results, including small sample size, insufficient randomization methods, poorly defined eligibility criteria, use of poly-herbal interventions, and variable breastfeeding practices among enrolled subjects. Given the insufficiency of evidence from these trials, no recommendation is made for the use of herbs as galactogogues. Well-designed and well-conducted clinical trials that address the above limitations are necessary to generate a body of evidence as a basis for recommendations regarding herbal galactogogues.

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Section: Resultsmentioning

confidence: 99%

“…Phytochemical screening of the plant reveals the presence of alkaloids, flavonoids, tannins, and saponins in its extracts. 18…”

Section: Resultsmentioning

confidence: 99%

Systematic Review of the Efficacy of Herbal Galactogogues

2013

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“…leaves ( CAL ) is recognized as a plant rich in several APM (Damanik, 2009) such as total phenolics, flavonoids, alkaloids, tannins, and saponins (Arumugam et al, 2016). It has been confirmed that mode of action of CAL covers cytotoxic, antioxidant, antimicrobial, antifungal, and antiparasitic effects (Hullatti et al, 2011;El-hawary et al, 2012;Selvakumar et al, 2012). CAL is also responsible for anti-inflammatory and anti-tumor activities in rats due to the presence of alkaloids, flavonoids, and saponins fractions (Chen et al, 2014;Ramalakshmi et al, 2014).…”

Section: Introductionmentioning

confidence: 99%

Coleus amboinicus (Lour.) leaves as a modulator of ruminal methanogenesis and biohydrogenation in vitro

Yanza

Szumacher-Strabel

Bryszak

et al. 2018

Journal of Animal Science

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Active plant metabolites (APM) are recognized as modifiers of ruminal microbial fermentation including methanogenesis and biohydrogenation of fatty acids (FA). Coleus amboinicus Lour. leaves (CAL) are rich in several APM, which could serve as ruminal fermentation modulators. A phytochemical analysis showed that CAL contain phenolic acids (10.4 mg·g-1 dry matter [DM]; high in rosmarinic acid), flavonoids (2.6 mg·g-1 DM), diterpenes (2 mg·g-1 DM), and linolenic acid (35.4 g (100 g)-1 FA). This study aimed to investigate the effect of CAL on ruminal methanogenesis and biohydrogenation as well as basic fermentation characteristics and microbial populations. The in vitro experiment was carried out using Hohenheim gas test system with 40 mL of buffered ruminal fluid incubated for 24 h at 39 °C in anaerobic conditions. Approximately 400 mg (DM basis) of total mixed ration (TMR) was used as a control substrate and the CAL substrate was used at doses of 10, 20, 40, and 80 mg DM replacing equal amounts of TMR. Addition of CAL decreased methane production up to 30% linearly as the amount of CAL increased (P < 0.05). In vitro dry matter digestibility and ammonia tended to increase with increasing doses of CAL. Concentration of total volatile fatty acids was not affected by the CAL although there appeared to be a minor positive linear trend; however, acetate, butyrate, and isobutyrate proportion increased quadratically (P < 0.001). CAL tended to linearly increase α-linolenic acid and conjugated linoleic acid as well as increased stearic acid concentration in buffered ruminal fluid. CAL particularly increased total protozoa and bacterial populations during fermentation, but inhibited methanogens. It is concluded that the CAL may be promising to be used as a feed additive to decrease methanogenesis as well as biohydrogenation of FA in the rumen.

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“…This can be caused by the presence of antioxidant compounds other than flavonoids. Based on previous research on the composition of the chemical content of Torbangun leaves (Hullatti and Bhattacharjee, 2011), it was found that in this leaf contains essential oils of 0.043% in fresh leaves or 0.2% in dried leaves. The results of the chromatogram analysis from Torbangun leaves were carried out by Suryowati et al (2015) showed the levels of chemical compounds n. Hexadecanoic acid (C 16 H 12 O 2 ) was reported to have biological activity as an antioxidant.…”

Section: Resultsmentioning

confidence: 99%

Application of microwave assisted extraction in extracting Torbangun leaves (Coleus ambonicus, L.) and its effects on polyphenol and flavonoids content

Hendrawan

Pramesi

Rachmawati

et al. 2018

AFSSAAE

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Flavonoids Microwave Assisted Extraction Polyphenols Torbangun Leaves Torbangun leaves (Coleus ambonicus, L.) contain polyphenol compounds, flavonoids and antioxidant compounds that can be obtained by extraction methods. However, with the conventional extraction method it has the disadvantage of long extraction time and requires a lot of solvents. Therefore, this study discusses the use of microwave assisted extraction (MAE) method to extract the leaves of Torbangun. This study uses two treatment factors on MAE i.e. power variations (100, 180 and 300 Watts) and extraction time (1, 2 and 3 minutes). This study aims to analyze the effect of MAE on the content of polyphenol compounds and flavonoids in the extraction process of Torbangun leaf. The results showed that the highest total phenol (4196.59 mg GAE/g extract) was found in the treatment of 300 watt of power with extraction time of 3-minutes with IC50 value of 9.89 mg/ml. The highest total flavonoid value was 300 watt of power with 1-minute extraction time which was 4.54 mg QE/g DW.

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Pharmacognostical Evaluation of Different Parts of Coleus amboinicus lour., Lamiaceae

Cited by 13 publications

References 6 publications

Systematic Review of the Efficacy of Herbal Galactogogues

Systematic Review of the Efficacy of Herbal Galactogogues

Coleus amboinicus (Lour.) leaves as a modulator of ruminal methanogenesis and biohydrogenation in vitro

Application of microwave assisted extraction in extracting Torbangun leaves (Coleus ambonicus, L.) and its effects on polyphenol and flavonoids content

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