Pharmacognostical Profile of Gymnema sylvestre and its Anti-Hyperglycemic Activity

Abstract

In this paper explored the pharmacognostical profile of gymnema sylvestre and its anti-hyperglycemic activity has been documented well with references. The importance of the species in Ayurveda has been highlighted. The bioactive components like gymnema sylvestre has a variety of secondary metabolites, including oleanane, gymnemic acid, gymnemasides (A-F), gymnemic acid (IXVIII) homologue, gymnemic acid A1 and its derivatives, triterpenoidsaponin, al has been clearly includedin the review kaloid (Conduritol-A), polypeptide (Gurmarin), and gymnemasaponins. This study has provided the groundwork for developing a pharmacognostical profile of medicinal plant growers and collectors. The goal of this review study is to provide a regional profile of the indigenous knowledge system for medicinal plant usage and cultural behaviors related to healing. This study aids in the identification of novel ethnomedicinal plant species in the study region, which may lead to the development of new medicines. The plant toxicity test results indicated that it may be used as an alternative to diabetes therapy with no or little adverse effects. This study confirms the conventional use of indigenous plant-derived natural medicine for treating diabetes mellitus. The study also highlighted the efficacy of "Ayurveda" which is an ancient tradition, used in some parts of India. This ancient concept should be carefully evaluated in the light of modern medical science and can be utilized partially if found suitable. I hope that this kind of research will be useful to future researchers as per their needs.

Exploring Antidiabetic Potential of Gymnema Sylvestre

“…It has been generally expressed that oxidative stress created because of free radicals 13,14 is engaged with the advancement of diabetes by pancreatic cell annihilation. 15,16 Assessed the methanolic leaf extract of GS on glucose transport and insulin resistance in vitro. The result showed that the extract enhanced in L6 myotubes, ameliorating the insulin resistance in 3T3 murine adipocyte cell line in-vitro.…”