Pharmacognostical Standardization of Stem Bark of Adenanthera pavonina L.

Hussain, Arshad; Hussain, Md. Sarfaraj; Rizvi, Aliza; Wahab, Shadma

doi:10.1016/s0975-3575(10)80100-2

Cited by 7 publications

(7 citation statements)

References 3 publications

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“…Several parts of the plant have been verified for its medicinal importance hence, the bark and leaves are used in the treatment of gonorrhea, ulcers and rheumatism. The powdered seeds are applied as a poultice to abscess and to promote suppuration (Hussain et al, 2010;Sujit et al, 2010). Physicochemical characterization of the seed oil showed appreciable amounts of neutral lipids and unsaturated fatty acids including linoleic, oleic and lignocerotic acids (Robert et al, 2004).…”

Section: Introductionmentioning

confidence: 99%

Effect of processing methods on the nutritional values and anti-nutritive factors of Adenanthera pavonina L. (Fabaceae) seeds

Nwafor¹,

Egonu²,

Nweze³

et al. 2017

Afr. J. Biotechnol.

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Section: Introductionmentioning

confidence: 99%

Effect of processing methods on the nutritional values and anti-nutritive factors of Adenanthera pavonina L. (Fabaceae) seeds

Nwafor¹,

Egonu²,

Nweze³

et al. 2017

Afr. J. Biotechnol.

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“…Antimicrobial agents in plants are secondary metabolites and are constantly present in active forms in all plants (Bereksi et al, 2018). Many plants have been used because of their antimicrobial traits, which are due to compounds synthesized in the secondary metabolism of the plant (Hussain et al, 2010). Plants have fantastic ability to produce a wide variety of secondary metabolites, like alkaloids, glycosides, terpenoids, saponins, steroids, flavonoids, tannins, quinones and coumarins (Manandhar et al, 2019).…”

Section: Introductionmentioning

confidence: 99%

In-vitro antibacterial activity of Boerhavia diffusa leaf extract against Staphylococcus aureus and Escherichia coli

Abhayarathna,

Mahendranathan

2024

Ceylon J. Sci.

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Plants are playing a significant role in maintaining human health and improving the wealth of human life and are a better alternative to synthetic drugs that display negative side effects, such as sensitization reactions, and disruption of the metabolic processes in the body via interaction with the body system. The main objective of this study was to evaluate the in-vitro antibacterial activity of Green Leafy Vegetable (GLVs), namely Boerhavia diffusa. Fully matured fresh leaf samples were collected from different localities in the Western Province, Sri Lanka. The acetone, ethanol and aqueous extracts of leaf samples were tested for antibacterial activity against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus), by using agar well diffusion method at the test concentrations of 0.25, 0.50 and 0.75 mg/μL. The maximum inhibitory effect was observed in the ethanol extracts of leaf samples against both bacterial strains at 0.75 mg/μL concentration. Ethanol extract of B. diffusa showed the maximum inhibition effect (17.8±0.3 mm) against S. aureus and it was the most susceptible bacteria than E. coli in plant extracts of all three solvents. All three extracts of B. diffusa showed most effective antibacterial activity against both bacterial strains, tested. The MIC values obtained from plants exhibited antibacterial activity ranged between 0.0625 and 0.25 mg/μL. The lowest MIC values were given by the ethanol extracts. Thus, the ethanol extract of this plant leaf sample was the most effective extract, which exhibited strong antimicrobial activity on both bacterial strains. Presence of bioactive compounds in these plant extracts could be the reason to indicate high antibacterial activity.

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“…Earlier phytochemical research has shown that the leaves contain octacosanol, dulcitol, beta-sitosterol glycosides, flavones and Stigmasterol and the alcoholic extract of the leaves contains an alkaloid. It is reported to have a large number of flavonoids, mainly gallic acid, terpenoids, tannins, sterols (beta-sitosterol, beta-sitosterol-3β-D-glucoside), triterpinoids (nonacosane and entriacontane) and saponins (sapogenins) [12,13]. Kigelia Africana (Bignoniaceae), known as the african sausage tree, is traditionally used as medicinal planteffective for a wide range of therapeutic activities, such as antidiabetic, anticancer, antimalarial, antibacterial, analgesic, antileprotic and antidiarrheal, anti-inflammatory, anti-urolithiasis, antioxidant, etc.…”

Section: Introductionmentioning

confidence: 99%

Development and Evaluation of Antidiabetic Polyherbal Tablet Using Medicinal Plants of Traditional Use

KOLHE¹,

Chaudhari²

2023

Int J Curr Pharm Sci

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The aim of the present study is to develop and evaluate polyherbal tablet prepared for the management of diabetes with enhanced disintegration time. The polyherbal extract prepared using methanolic extract of selected traditionally used medicinal plants such as Adenanthera pavonina, Kigelia africana, Parkia biglandulosa and Syzygium jambose (1:1:1:2) was evaluated in alloxan monohydrate induced diabetic rat model. The polyherbal tablets were prepared by wet granulation method with excipients microcrystalline cellulose; dicalcium phosphate dehydrate and sodium starch glycolate. After preformulation studies, tablets were evaluated by using weight variation, hardness, friability and disintegration time. The diabetic rats treated with polyherbal extract were compared with the diabetic control rats group. Positive results were obtained in the observed parameters, thus favoring the use of the plants. Pre-formulation study revealed that all the evaluated parameters were found to be within acceptable limits. The weight variation of the formulated tablets was 1.43 % RSD. The disintegration time of the formulations was found to be 9.50 min. The tablets also underwent accelerated stability over the period of three months. No marked changes were observed in all the parameters evaluated during three months of accelerated stability study. Laboratory-scale preparation of polyherbal tablet can lead to new powerful and stable oral dosage formulations for diabetes mellitus and lighten the synergistic area of action of herbs.

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Pharmacognostical Standardization of Stem Bark of Adenanthera pavonina L.

Cited by 7 publications

References 3 publications

Effect of processing methods on the nutritional values and anti-nutritive factors of Adenanthera pavonina L. (Fabaceae) seeds

Effect of processing methods on the nutritional values and anti-nutritive factors of Adenanthera pavonina L. (Fabaceae) seeds

<em>In-vitro </em>antibacterial activity of <em>Boerhavia diffusa</em> leaf extract against <em>Staphylococcus aureus </em>and<em> Escherichia coli</em>

Development and Evaluation of Antidiabetic Polyherbal Tablet Using Medicinal Plants of Traditional Use

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