2024
DOI: 10.21608/jcvr.2024.352712
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Pharmacokinetic and Bioavailability of Apramycin in Broiler Chickens.

Hasnaa Gad,
Taha Attia,,
Hanem Elgendy
et al.

Abstract: The pharmacokinetics inquiries of apramycin were evaluated after receiving a single intravenous (IV) and single oral (PO) dosage in healthy broiler chickens. The serum concentration was measured using high-performance liquid chromatography (HPLC). The kinetic parameters showed that apramycin suggested a two compartments open model following a single intravenous administration of 10 mg/kg b.wt, with distribution half-life (t0.5α) of 0.24 ± 0.04h, elimination half-life (t0.5β ) was 5.45 ± 0.47h, steady state vol… Show more

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