Pharmacokinetic changes of several antibiotics in chickens during induced fatty liver

Soback, S.; Gil, Ziv; Bogin, E.; Cohen, Zaza; Earon, Yehoshua

doi:10.1016/s0034-5288(18)30740-9

Cited by 8 publications

(13 citation statements)

References 8 publications

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“…, 2004). Serum protein binding in cats (11.24–17.68%) seems lower than that reported in other species such as sheep (30–40%), chickens (23%), and goats (43.7–55.6%) (Ziv & Sulman, 1973; Soback et al. , 1987; Abo El‐Sooud et al.…”

Section: Discussionmentioning

confidence: 63%

“…Elimination of lincomycin in cats was slower than that reported for other domestic species such as calves, chicken, and goats (Burrows et al. , 1986; Soback et al. , 1987; Abo El‐Sooud et al.…”

Section: Discussionmentioning

confidence: 67%

“…, 2001), sheep (Ziv & Sulman, 1973), goats (Abo El‐Sooud et al. , 2004), and chicken (Soback et al. , 1987).…”

Section: Introductionmentioning

confidence: 99%

“…Lincomycin pharmacokinetic profile has been described in some domestic animals, such as calves (Burrows et al, 1986), pigs (Nielsen & Gyrd-Hansen, 1998;Kuroha et al, 2001), sheep (Ziv & Sulman, 1973), goats (Abo El-Sooud et al, 2004, and chicken (Soback et al, 1987). However, to the authors' knowledge, there are no data on lincomycin pharmacokinetic in cats.…”

Section: Introductionmentioning

confidence: 99%

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Pharmacokinetics and bone tissue concentrations of lincomycin following intravenous and intramuscular administrations to cats

Albarellos

Montoya

Denamiel

et al. 2011

Vet Pharm & Therapeutics

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The pharmacokinetic properties and bone concentrations of lincomycin in cats after single intravenous and intramuscular administrations at a dosage rate of 10 mg/kg were investigated. Lincomycin minimum inhibitory concentration (MIC) for some gram-positive strains isolated from clinical cases was determined. Serum lincomycin disposition was best-fitted to a bicompartmental and a monocompartmental open models with first-order elimination after intravenous and intramuscular dosing, respectively. After intravenous administration, distribution was rapid (T(1/2(d)) = 0.22 ± 0.09 h) and wide as reflected by the volume of distribution (V((d(ss)))) of 1.24 ± 0.08 L/kg. Plasma clearance was 0.28 ± 0.09 L/h · kg and elimination half-life (T(1/2)) 3.56 ± 0.62 h. Peak serum concentration (C(max)), T(max), and bioavailability for the intramuscular administration were 7.97 ± 2.31 μg/mL, 0.12 ± 0.05 h, and 82.55 ± 23.64%, respectively. Thirty to 45 min after intravenous administration, lincomycin bone concentrations were 9.31 ± 1.75 μg/mL. At the same time after intramuscular administration, bone concentrations were 3.53 ± 0.28 μg/mL. The corresponding bone/serum ratios were 0.77 ± 0.04 (intravenous) and 0.69 ± 0.18 (intramuscular). Lincomycin MIC for Staphylococcus spp. ranged from 0.25 to 16 μg/mL and for Streptococcus spp. from 0.25 to 8 μg/mL.

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Section: Discussionmentioning

confidence: 63%

Section: Discussionmentioning

confidence: 67%

“…, 2001), sheep (Ziv & Sulman, 1973), goats (Abo El‐Sooud et al. , 2004), and chicken (Soback et al. , 1987).…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Pharmacokinetics and bone tissue concentrations of lincomycin following intravenous and intramuscular administrations to cats

Albarellos

Montoya

Denamiel

et al. 2011

Vet Pharm & Therapeutics

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show abstract

“…, 1983), dogs (Brown et al. , 1975), pigs (Chaleva & Nguyen, 1987), and chickens (Soback et al. , 1987).…”

Section: Mean ± Se Of the Pharmacokinetic Parameters Of Lincomycin Almentioning

confidence: 99%

Lack of pharmacokinetic interaction between lincomycin and aspirin in healthy goats

Abo‐EL‐Sooud

Goudah

El‐Aty

2004

Vet Pharm & Therapeutics

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Biochemical Alterations in Liver Diseases of Domestic Animals

Bogin

1989

Clinical Chemistry

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Pharmacokinetic changes of several antibiotics in chickens during induced fatty liver

Cited by 8 publications

References 8 publications

Pharmacokinetics and bone tissue concentrations of lincomycin following intravenous and intramuscular administrations to cats

Pharmacokinetics and bone tissue concentrations of lincomycin following intravenous and intramuscular administrations to cats

Lack of pharmacokinetic interaction between lincomycin and aspirin in healthy goats

Biochemical Alterations in Liver Diseases of Domestic Animals

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