2012
DOI: 10.3851/imp2347
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Pharmacokinetics of Darunavir/Ritonavir in Asian HIV-1-Infected Children Aged ≥7 Years

Abstract: Thai children aged ≥7 years who were on standard darunavir dosing with 100 mg ritonavir boosting had adequate and comparable darunavir AUC(0-12), C(max) and C(12) to non-Asian children who mainly used lower doses of ritonavir boosting. A ritonavir boosting dose of 100 mg can be used for children weighing ≥20 kg, particularly when lower dose formulations are unavailable or if intolerant to the solution.

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“…Acyclovir [43] Preterm and term infants Population Yes Darunavir/ritonavir [44] Children Non-compartmental…”
Section: Population Yesmentioning
confidence: 99%
“…Acyclovir [43] Preterm and term infants Population Yes Darunavir/ritonavir [44] Children Non-compartmental…”
Section: Population Yesmentioning
confidence: 99%