2011
DOI: 10.1055/s-0031-1296226
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Pharmacokinetics of felodipine extended-release tablets in healthy Taiwanese subjects: a retrospective review

Abstract: The objective of this study was to investigate the pharmacokinetics of felodipine (CAS 72509-76-3) in healthy male Taiwanese subjects. This is a retrospective review of five felodipine pharmacokinetic studies completed in Taiwan. A total of 100 evaluable healthy Taiwanese males were enrolled in these studies. The subjects received 5 mg (n = 80) or 10 mg (n = 20) of Plendil? (felodipine extended-release tablets; felodipine ER) once daily for 6 days. The mean ? SD tmax, ss, Cmax, ss and AUC? of dose normalized t… Show more

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