2019
DOI: 10.1002/dta.2568
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Pharmacokinetics of selegiline, R‐methamphetamine, R‐amphetamine, and desmethylselegiline in oral fluid after a single oral administration of selegiline

Abstract: Background Chiral analysis is a crucial way to differentiate selegiline (SG) intake from drug abuse. Oral fluid (OF) has been successfully used as an alternative matrix for blood testing in several pharmacokinetic studies. Objective The aim of this study is to describe the pharmacokinetics of SG and its main metabolites in OF after a single oral administration of SG which is meaningful for results interpretation in forensic analysis. Methods Ten milligrams of SG were orally administered to 8 volunteers, and OF… Show more

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