Pharmacokinetics of Tildipirosin in Healthy and Mycoplasma gallisepticum Infected Chickens

doi:10.47278/journal.ijvs/2021.047

Cited by 2 publications

(1 citation statement)

References 15 publications

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“…I nfectious diseases have always been a great threat in intensive animal production systems (Bosila et al, 2021;Guerrini et al, 2021;Saeed 2021;Tahir et al, 2021, Ul-Rahman et al, 2021Abu et al, 2022). Use of antibiotics in broiler diet has been known to have an important role in reduction of the intestinal pathogens and diseases incidences (Elazab et al, 2021). However, now consumers are more concerned about the residue of antibiotics in poultry eggs and meat (Mathur and Singh, 2005).…”

Section: Introductionmentioning

confidence: 99%

Prebiotic, probiotic, and antibiotic growth promoters use in commercial broilers: A comparative study

Ali,

Qureshi,

Rehan

et al. 2023

J Hellenic Vet Med Soc

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The objective of this study was to observe the effect of Mannan oligosaccharides (MOS), a prebiotic, in the replacement of the antibiotics in the broilers. For this purpose, two hundred broiler chicks were bought from a hatchery and allocated into five treatments having four replicates (10 birds in each). Birds were distributed into five groups; control, antibiotics (Zinc Bacitracin 10%), probiotics (Bacillus subtilis) and prebiotics (MOS), and a combination of probiotics and prebiotics groups. Five iso-nitrogenous and iso-caloric diets were prepared and offered to birds. Feed intake and body weight were recorded. At the end of the trial, birds were slaughtered to obtain carcass and gut health data. Data collected were examined by ANOVA under CRD and mean values were compared using Tukey’s HSD (Honestly significant difference) test. Weight gain was higher (P<0.05) in birds fed diet having probiotics and prebiotics in a combination form. Improved (P<0.05) FCR was recorded in birds fed diet having prebiotics alone and in combination with probiotics. The dressing percentage was higher (P<0.05) in birds fed diet having Probiotics + Prebiotics and control birds. Chest yield was higher (P<0.05) in birds fed having Probiotics + Prebiotics. In gut morphometric parameters, there was observed an increase in villus height, and a significant change of increase in villus surface area was seen. In conclusion, the addition of prebiotics in combination with probiotics, in feed, remarkably improved growth performance and carcass yield in commercial broilers.

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Section: Introductionmentioning

confidence: 99%

Prebiotic, probiotic, and antibiotic growth promoters use in commercial broilers: A comparative study

Ali,

Qureshi,

Rehan

et al. 2023

J Hellenic Vet Med Soc

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Improving Growth, Digestive and Antioxidant Enzymes and Immune Response of Juvenile Grass Carp (Ctenopharyngodon idella) by Using Dietary Spirulina platensis

Faheem

Jamal

Nazeer

et al. 2022

Fishes

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The present study was designed to investigate the effect of Spirulina platensis (SP) supplemented diets on the growth performance, digestive enzymes, hepatic antioxidants and innate immunity biomarkers in juvenile grass carp (Ctenopharyngodon idella). Two hundred and forty grass carp juveniles (average weight 4.81 ± 0.13 g) were divided into four treatment groups in triplicates (20 fish/replicate) and fed with diets containing 0, 1, 5, and 10% Spirulina for 90 days. A significant increase in growth (p < 0.05) was observed in fish fed with diets having 1 and 5% Spirulina. Intestinal protease and lipase activities increased significantly (p < 0.01) in fish fed with a diet having 5% Spirulina while intestinal amylase activity increased significantly (p < 0.01) in fish fed with diets having 1, 5, and 10% Spirulina. Hepatic lipid peroxidation decreased significantly (p < 0.05) in fish fed with a 1 and 5% Spirulina supplemented diet. The activity of catalase, glutathione-S-transferase, and glutathione levels increased significantly (p < 0.05) in the livers of fish fed with 1% Spirulina supplemented diets while no significant difference (p > 0.05) was observed for hepatic superoxide dismutase levels when compared to the control. Significant increases in the skin mucus protease (p < 0.05), antiprotease (p < 0.01), lysozyme (p < 0.001), and peroxidase (p < 0.05) activities were observed in fish fed with 5% Spirulina-supplemented diets. Gene expression analysis of head kidney showed that fish fed with a 1% Spirulina diet had significantly (p < 0.01) higher expression of tnf-α, il-8, and inf-γ. In conclusion, the present study suggested that the inclusion of 5% Spirulina platensis in the diet of grass carp has positive effects on growth, digestive enzymes, antioxidants, and innate immunity.

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Pharmacokinetics of Tildipirosin in Healthy and Mycoplasma gallisepticum Infected Chickens

Cited by 2 publications

References 15 publications

Prebiotic, probiotic, and antibiotic growth promoters use in commercial broilers: A comparative study

Prebiotic, probiotic, and antibiotic growth promoters use in commercial broilers: A comparative study

Improving Growth, Digestive and Antioxidant Enzymes and Immune Response of Juvenile Grass Carp (Ctenopharyngodon idella) by Using Dietary Spirulina platensis

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