Pharmacologic Treatment of Cognitive Deficits and Hypersexuality Due to “Shaken-Baby Syndrome”

Schmidt, John G.; Schneider, William N.

doi:10.1177/154596830001400209

Cited by 9 publications

(6 citation statements)

References 29 publications

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“…Significant improvements in both hypersexuality and hyperactivity have been achieved. After discontinuation of propranolol (patient's decision), the problem of hypersexuality returned (Schmidt and Schneider, 2000). The use of propranolol can bring many benefits to patients with minimal side effects, but so far there are no data on its use among adults.…”

Section: Beta-blockersmentioning

confidence: 99%

Hypersexuality and pharmacological treatment options

Kocyan

Knapik

Kozłowska

et al. 2020

Pharmacotherapy in Psychiatry and Neurology

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concerning the treatment of excessive sexual activity disorders. Specific mechanisms underlying hypersexu ality and the consequent potential differences in its treatment were considered. Literature review. The classification of sexual dis orders related to excessive sexual activity is rather problematic. Both DSM-5 and ICD-11 lack in a homogenous classification of this disorder. Currently, the safest and most beneficial drugs for patients with non-paraphilic disorders seem to be SSRI medications. Drugs presenting an antiandrogenic action (LHRH) are not recommended due to their side effects, apart from cases proceeding with severe symptoms. Promising results were obtained in a trial with naltrexone; yet, the study did not fulfil methodological norms. Other medications used in the treatment of hypersexuality are of minor importance; however, they may be used especially when psychiatric comorbidities are present. Conclusions. The best effects in the treatment of compulsive sexual behaviour are obtained with the combination of psychotherapy and SSRI drugs. Few methodologically correct studies have been performed. Most studies are carried out on small groups and fail to use methods which would enable to compare various therapeutic options. Research on the pharmacotherapy of non-paraphilic hypersexuality should be continued, especially regarding drugs which may act on the obsessive-compulsive mechanism.

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Section: Beta-blockersmentioning

confidence: 99%

Hypersexuality and pharmacological treatment options

Kocyan

Knapik

Kozłowska

et al. 2020

Pharmacotherapy in Psychiatry and Neurology

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show abstract

“…The patient’s hypersexuality was later successfully treated with amantadine and propranolol. 3 Thus, it initially appears that dextroamphetamine was not the cause of the patient’s paroxysmal hypersexuality. There is a commonly held belief among the lay public that amphetamines stimulate the sex drive.…”

Section: Casementioning

confidence: 99%

The Association Between Pharmacologic Drug Intoxication and Forensic-Specific Intent

Yoshizuka

Perry

2012

Journal of Pharmacy Practice

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Two criminal cases are presented in which the counsel for the defendants requested an expert witness to opine whether their drug-intoxicated clients were capable of forming the specific intent necessary to commit the felonies for which they were charged. Intent from a legal standpoint is often times a poorly understood concept among expert witnesses. The application of a criminal defense of intoxication depends upon the nature of the crime the defendant is accused. The intoxication defense cannot be applied to general intent crimes. In cases where specific intent crimes are charged against the defendant, voluntary intoxication may be used to prove that the defendant could not possess the capacity to formulate the intent as a necessary element of the crime. Voluntary intoxication may be used as a defense in specific intent crimes to negate the critical element of intent required for the prosecution to prove in criminal cases. Without being able to prove intent, the prosecution has not met their burden of proving that every element of the crime has been met, thus resulting in an acquittal.

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“…For muscular spasticity, intrathecal baclofen (Turner, 2003) or botulinum toxin (Guettard et al, 2009) may be prescribed. To help with attention, amantadine is useful in some patients (Schmidt & Schneider, 2000; Williams, 2007). If there has been pituitary damage, hormone replacement may be needed (Acerini & Tasker, 2007).…”

Section: Longer‐term Interventionsmentioning

confidence: 99%

Practitioner Review: Beyond shaken baby syndrome: what influences the outcomes for infants following traumatic brain injury?

Ashton

2010

Child Psychology Psychiatry

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Pharmacologic Treatment of Cognitive Deficits and Hypersexuality Due to “Shaken-Baby Syndrome”

Abstract: Cognitive deficits and hypersexuality with hyperactive features due to shaken-baby syndrome may respond to the drug regimen of amantadine and propranolol.

Cited by 9 publications

References 29 publications

Hypersexuality and pharmacological treatment options

Hypersexuality and pharmacological treatment options

The Association Between Pharmacologic Drug Intoxication and Forensic-Specific Intent

Practitioner Review: Beyond shaken baby syndrome: what influences the outcomes for infants following traumatic brain injury?

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