Pharmacological actions of <i>Cordyceps</i>, a prized folk medicine

Ng, T.B.; Wang, H X

doi:10.1211/jpp.57.12.0001

Cited by 302 publications

(188 citation statements)

References 104 publications

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“…Traditional Chinese medicine believes that C. militaris can be used to treat impotence, seminal emission, and infertility, and invigorate kidney and lungs [Ch 2000;Zhu et al 1998]. Pharmacological studies have confirmed that C. militaris possesses a wide range of biological activities including anti-bacterial, anti-tumor, anti-oxidation, and immune-modulatory [Liu et al 1994;Ng and Wang 2005;Reis et al 2013]. It can also improve reproductive function and repair reproductive dysfunction induced by cyclophosphamide in mice [Jin and Chen 2008].…”

Section: Introductionmentioning

confidence: 99%

Protective effect of Cordyceps militaris extract against bisphenol A induced reproductive damage

Wang

Chen

Jiang

et al. 2016

Systems Biology in Reproductive Medicine

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Section: Introductionmentioning

confidence: 99%

Protective effect of Cordyceps militaris extract against bisphenol A induced reproductive damage

Wang

Chen

Jiang

et al. 2016

Systems Biology in Reproductive Medicine

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“…These entomopathogenic fungi have a wide spectrum of pharmacological activities (Ng & Wang, 2005). It shows antioxidant, anti-inflammatory, antitumor, antiociceptive, antifibrotic and antiangiogenic activities (Ng & Wang, 2005), and immunopotentiation properties (Kuoet al, 2007). C. militaris was reported to improve insulin resistance and insulin secretion (Cheng et al, 2012).…”

Section: Introductionmentioning

confidence: 99%

Fermentation products of <i>Cordyceps militaris</i> enhance performance and modulate immune response of weaned piglets

Cheng¹,

Wen²,

Dybus³

et al. 2016

SA J. An. Sci.

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The aim of this study was to investigate the effect of supplementation of Cordyceps militaris fermentation products (CMF) on growth performance and immunocompetence of piglets. The study involved three groups of animals, which were supplemented with CMF (500, 1000 and 1500 μg/kg feed), and a control group. CMF supplementation significantly increased growth performance in weaned piglets. Bodyweight gain, average daily gain and feed intake in animals supplemented with 1000 µg CMF/kg feed were significantly higher in comparison with the control group. In addition, CMF supplementation only significantly increased the synthesis of Th1 cytokines, as indicated by the levels of IL-2 and IFN-γ. The piglets fed with the CMF supplement displayed an increased cellular immune response. Indeed, alveolar macrophages isolated from piglets supplemented with 1000 and 1500 µg CMF/kg feed had significantly higher chemotactic and phagocytic indices than those isolated from piglets that received the control feed or feed supplemented with 500 µg CMF/kg. In relation to the absence of effect on Th2 cytokines, the CMF supplement had no effect on hog cholera antibody titre. In summary, feed supplementation with CMF improves growth performance and enhances cell-mediated immunity. CMF supplementation may thus be useful at weaning to counteract physiological and immunological stress during this period. ______________________________________________________________________________________

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“…Stimulation of erythropoiesis has been reported as well as well as antibacterial, anti-fungal and anti-microbial activity (Ng and Wang, 2005).…”

Section: Other Effectsmentioning

confidence: 99%

Cordyceps, an Endangered Medicinal Plant: A Short Review

Tah¹

2017

WJPPS

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Cordyceps is a genus of a fungi (sac fungi) that includes about 400 species. All Cordyceps species are endoparasitoids, parasitic mainly on insects and other arthropods (they are thus entomopathogenic In 2007, nuclear DNA sampling revealed this species to be unrelated to most of the rest of the members of the genus; as a result it was renamed Ophiocordyceps sinensis and placed in a new family, the Ophiocordycipitaceae.The generic name Cordyceps is derived from the Greek word kordyle, meaning "club", and the Latin stem -ceps, meaning "head". Several species of Cordyceps are considered to be medicinal mushrooms in classical Asian pharmacologies, such as that of traditional Chinese (Halpern, 2007; and Tibetan medicines.When a Cordyceps fungus attacks a host, the mycelium invades and eventually replaces the host tissue, while the elongated fruit body (ascocarp) may be cylindrical, branched, or of complex shape. The ascocarp bears many small, flask-shaped perithecia containing asci.These, in turn, contain thread-like ascospores, which usually break into fragments and are presumably infective. Some current and former Cordyceps species are able to affect the behavior of their insect host: Ophiocordyceps unilateralis (formerly Cordyceps unilateralis) causes ants to climb a plant and attach there before they die. This ensures the parasite's environment is at an optimal temperature and humidity, and that maximal distribution of the spores from the fruit body that sprouts out of the dead insect is achieved (Hughes et al.,

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Pharmacological actions of Cordyceps, a prized folk medicine

Cited by 302 publications

References 104 publications

Protective effect of Cordyceps militaris extract against bisphenol A induced reproductive damage

Protective effect of Cordyceps militaris extract against bisphenol A induced reproductive damage

Fermentation products of <i>Cordyceps militaris</i> enhance performance and modulate immune response of weaned piglets

Cordyceps, an Endangered Medicinal Plant: A Short Review

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