2021
DOI: 10.1016/j.jep.2021.113777
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Pharmacological activity and flavonoids constituents of Artemisia judaica L aerial parts

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Cited by 26 publications
(21 citation statements)
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“…Terpenes comprise hinokitiol, mesitylene, eugenol, and ursolic acid, while terpenoid compounds include artemisinin, which possesses anthelmintic activity against round worms and potent anti-cancer activity [ 67 , 91 ] Moreover, both ursolic acid and eugenol have been shown to exhibit anti-inflammatory, antitumor, antiviral, and antimicrobial effects [ 92 , 93 ]. From literature, it was found that vitexin, orientin, quercetin, luteolin, apigenin, diosmetin, isoferulic acid, caffeic acid, santolina alcohol, mesitylene, and eugenol have been previously reported in A. judaica L. [ 8 , 11 , 13 , 94 , 95 ]. Betulinic acid was reported as an effective medicinal agent for the treatment of malignant melanoma [ 62 ], while alkaloid piperine has demonstrated anti-inflammatory and hypoglycemic effects [ 96 ].…”
Section: Resultsmentioning
confidence: 99%
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“…Terpenes comprise hinokitiol, mesitylene, eugenol, and ursolic acid, while terpenoid compounds include artemisinin, which possesses anthelmintic activity against round worms and potent anti-cancer activity [ 67 , 91 ] Moreover, both ursolic acid and eugenol have been shown to exhibit anti-inflammatory, antitumor, antiviral, and antimicrobial effects [ 92 , 93 ]. From literature, it was found that vitexin, orientin, quercetin, luteolin, apigenin, diosmetin, isoferulic acid, caffeic acid, santolina alcohol, mesitylene, and eugenol have been previously reported in A. judaica L. [ 8 , 11 , 13 , 94 , 95 ]. Betulinic acid was reported as an effective medicinal agent for the treatment of malignant melanoma [ 62 ], while alkaloid piperine has demonstrated anti-inflammatory and hypoglycemic effects [ 96 ].…”
Section: Resultsmentioning
confidence: 99%
“…It is also recommended for the treatment of skin disorders, weak immune systems, digestive system disorders, diabetes, inflammatory-related diseases, fungal infections, and arthritis [ 6 , 7 , 8 ]. Phytochemical investigations of A. judaica L. have revealed the presence of different chemical classes, terpenes, polyphenols, flavonoids, and bitter principles [ 8 , 9 , 10 , 11 ]. Several scientific reports have handled the biological activities of the crude extract, fractions of different polarities, isolated active fractions, or pure compounds.…”
Section: Introductionmentioning
confidence: 99%
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“…In Saudi Arabia, ArJ grows in the kingdom’s northern region, including the border area of the Hail-Qassim regions [ 21 ]. ArJ has been reported for several traditional uses, e.g., healing external wounds and repairing snake and scorpion bites [ 22 ]. In addition, ArJ is traditionally used to treat gastrointestinal disorders, sexual inability, hyperglycemia, heart diseases, inflammatory disorders, arthritis, cancers [ 1 , 20 ], skin diseases, atherosclerosis, and enhance vision and immunity [ 23 , 24 ].…”
Section: Introductionmentioning
confidence: 99%
“…The Bedouins in Egypt (Sinai) and Saudi Arabia also use the plant as a herbal tea in treating GIT disorders [ 16 ]. Biologically, ArJ demonstrated antidiabetic, antioxidant, hepatoprotective, and anti-inflammatory activities in experimental animals [ 22 , 25 , 26 ] due to the properties inherent in the chemical structure of the compounds it contains [ 27 ]. The plant also exhibited weak antimicrobial activity against Gram-positive and Gram-negative bacteria [ 28 , 29 ].…”
Section: Introductionmentioning
confidence: 99%