Pharmacological interventions for preventing atrial fibrillation after lung surgery: systematic review and meta-analysis

Wang, Xiaomei; Zhang, Demei; Ren, Yang; Han, Jingjing; Li, Guangling; Guo, Xiaodong

doi:10.1007/s00228-022-03383-2

Cited by 4 publications

(2 citation statements)

References 41 publications

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“…This was supported by a meta-analysis conducted by Zhao et al, focusing on patients undergoing general thoracic surgery, which confirmed the superior preventive benefits of β-blockers in this setting ( 69 ). The findings were also corroborated by another meta-analysis by Wang et al ( 70 ). In specific high-risk patients undergoing NCS, the use of perioperative low-dose bisoprolol patches proved effective in preventing POAF ( 71 ).…”

Section: Introductionsupporting

confidence: 76%

Exploring postoperative atrial fibrillation after non-cardiac surgery: mechanisms, risk factors, and prevention strategies

Jiang,

Liao,

Chen

et al. 2023

Front. Cardiovasc. Med.

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Atrial fibrillation (AF) stands as the most prevalent persistent arrhythmia and a common complication after surgical procedures. Although the majority of non-cardiac surgery patients experience postoperative AF (POAF) and the condition is typically self-limited and asymptomatic, its detrimental impact on patient outcomes, prolonged hospitalization, and heightened risk of stroke and overall mortality has become increasingly evident. Of significant concern, POAF emerges as a noteworthy risk factor for stroke, myocardial infarction, and mortality in comparison to patients with non-surgical atrial fibrillation. Multiple studies have corroborated the association between POAF and an elevated risk of stroke and mortality. The development of postoperative atrial fibrillation is multifactorial, with the inflammatory response being a primary contributor; additionally, factors such as hypovolemia, intraoperative hypotension, anemia, trauma, and pain can trigger POAF. Risk factors for POAF in non-cardiac surgery primarily relate to age, hypertension, obesity, prior cardiac disease, obstructive sleep apnea, and male sex. Prophylactic treatment with β-blockers, amiodarone, or magnesium has demonstrated efficacy, but further trials are warranted, especially in high-risk populations. This review provides an account of the incidence rate, pathophysiology, and prognosis of atrial fibrillation after non-cardiac surgery, elucidates the underlying mechanisms of its occurrence, and explores various preventive strategies investigated in this domain.

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Section: Introductionsupporting

confidence: 76%

Exploring postoperative atrial fibrillation after non-cardiac surgery: mechanisms, risk factors, and prevention strategies

Jiang,

Liao,

Chen

et al. 2023

Front. Cardiovasc. Med.

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show abstract

“…There are also data on the use of losartan, beta-blockers, magnesium sulfate, or calcium-channel blockers in the prevention of perioperative AF. According to the literature, prophylaxis with beta-blockers seems to be the most effective and safest of the treatments studied [46,47].…”

Section: Management Of Supraventricular Arrhythmias In Lung Cancer Pa...mentioning

confidence: 99%

Cardiac Arrhythmias in Patients Treated for Lung Cancer: A Review

Hawryszko,

Sławiński,

Tomasik

et al. 2023

Cancers

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Cardio-oncology currently faces one of the greatest challenges in the field of health care. The main goal of this discipline is to ensure that patients treated for cancer do not suffer or die from cardiovascular disease. The number of studies on the mechanisms of heart injury during cancer treatment is constantly increasing. However, there is insufficient data on heart rhythm disorders that may result from this treatment. This issue seems to be particularly important in patients with lung cancer, in whom anticancer therapy, especially radiotherapy, may contribute to the onset of cardiac arrhythmias. The observed relationship between cardiac dosimetry and radiotherapy-induced cardiotoxicity in lung cancer treatment may explain the increased mortality from cardiovascular causes in patients after chest irradiation. Further research is essential to elucidate the role of cardiac arrhythmias in this context. Conversely, recent reports have highlighted the application of stereotactic arrhythmia radioablation (STAR) in the treatment of ventricular tachycardia. This review of available studies on the epidemiology, pathogenesis, diagnosis, and treatment of arrhythmias in patients treated for lung cancer aims to draw attention to the need for regular cardiological monitoring in this group of patients. Improving cardiac care for patients with lung cancer has the potential to enhance their overall therapeutic outcomes.

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New Predictive Model of Perioperative Atrial Fibrillation for Thoracic Surgery Is Needed

Liang,

Mei

2024

The Annals of Thoracic Surgery

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Pharmacological interventions for preventing atrial fibrillation after lung surgery: systematic review and meta-analysis

Cited by 4 publications

References 41 publications

Exploring postoperative atrial fibrillation after non-cardiac surgery: mechanisms, risk factors, and prevention strategies

Exploring postoperative atrial fibrillation after non-cardiac surgery: mechanisms, risk factors, and prevention strategies

Cardiac Arrhythmias in Patients Treated for Lung Cancer: A Review

New Predictive Model of Perioperative Atrial Fibrillation for Thoracic Surgery Is Needed

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