Pharmacological Study and Fractionation of Paspalum Scrobiculatum Extract

Bhide, N K

doi:10.1111/j.1476-5381.1962.tb01145.x

Cited by 15 publications

(8 citation statements)

References 7 publications

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“…Porridge, chapatti (flat cake or bread made from flour), sprouted grains, dosa (a thin fermented pancake containing blackgram), and popped grains are some of the most common foods prepared from the millets (Dwivedi et al, 2012 and references therein). Both fungi produce cyclopiazonic acid, which causes kodua poisoning (Rao and Husain, 1985), which results in sleepiness, tremors, and giddiness in humans (Bhide, 1962). To date, no antinutrients from barnyard and kodo millets have been reported.…”

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confidence: 99%

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Forming Core Collections in Barnyard, Kodo, and Little Millets using Morphoagronomic Descriptors

et al. 2014

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2673ReseaRch M illets, which are comprised of a number of C 4 smallgrained, annual cereal grasses including barnyard millet, kodo millet, and little millet have abundant within-species racial diversity. These species also differ in ploidy levels. The ploidy levels in barnyard millet range from tetraploid to hexaploid to octaploid, while kodo and little millets are tetraploids (de Wet et al., 1983;Wanous, 1990). Barnyard millet has two distinct cultivated species, the Indian barnyard millet [E. colona (L.) Link] and Japanese barnyard millet [E. crus-galli (L.) Beauv], each with two Abbreviations: CB, culm branching; CR%, coincidence rate; CT, culm thickness; DF, days to 50% flowering; FL, fruit length; FLBL, flag leaf blade length; FLBW, flag leaf blade width; FLSL, flag leaf sheath length; FW, fruit width; G × E, genotype × environment; GH, growth habit; H´, Shannon-Weaver diversity index; IL, inflorescence length; LLR, length of lowest raceme; LRL, longest raceme length; MD%, mean difference percentage; NBT, number of basal tillers; NL, number of leaves; NNPAI, number of nodes on primary axis of inflorescence; NRAT, number of racemes above thumb; NRI, number of racemes per inflorescence; NSIB, number of secondary inflorescence branches; OPAS, overall plant aspects score; PE, panicle exsertion; PH, plant height; PL, peduncle length; PP, plant pigmentation; TL, thumb length; VD%, variance difference percentage; VR% variable rate.

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confidence: 99%

“…However, kodua poisoining was reported when kodo millet grains infected with Aspergillus flavus or A. tamarii were used as food or feed. Both fungi produce cyclopiazonic acid, which causes kodua poisoning (Rao and Husain, 1985), which results in sleepiness, tremors, and giddiness in humans (Bhide, 1962).…”

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confidence: 99%

Forming Core Collections in Barnyard, Kodo, and Little Millets using Morphoagronomic Descriptors

et al. 2014

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“…PCA9 was effective in reducing amphetamine-induced hypera ctivity though it did not prevent the toxicity in aggregated mice. However, similar ob servations have been reported for some neuroleptics (21,22). PCA9 showed specific block of the conditioned avoidance response in rats and sup pressed fighting behaviour in mice; the ED50s for these effects were much lower than the ED,, which impaired coordinated motor activity (Table 4) These actions of PCA9 simu late those of major tranquillizers (chlorpromazine and reserpine) which have been report ed to block CAR in rats (10) and suppress fighting behaviour in mice (23,24).…”

Section: Acute Toxicitymentioning

confidence: 93%

PHARMACOLOGICAL STUDY OF 1-(β-PHENYLETHYL) TRIAZOLO (4, 5-c) PYRIDINE HYDROCHLORIDE, A TRANQUILLIZING AGENT

1967

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In an investigation of the pharmacological activities of a large number of substituted diaminopyridine and the corresponding imidazo and triazolo pyridines it was found that imidazo and triazolo (c) pyridines, in general, produced central depressant action and amongst these 1-((3-phenylethyl) triazolo (4,5-c) pyridine hydrochloride (PCA9) showed relatively better sedative and tranquillizing effects in mice (1, 2). In view of the tranquil lizing activity of PCA9 a study on some neuro-psychopharmacological and other phar macodynamic effects of this compound was carried out to elucidate the pattern of activity and the results of which are embodied in the present communication. MATERIALS AND METHODSSolution of 1-((3-phenylethyl) triazolo (4,5-c) pyridine hydrochloride (PCA9) was injected intraperitoneally (0.2 ml/20 g body weight) into white mice (16-20 g) and rats (100-140 g) of either sex from the C.D.R.I. colony. All experiments were conducted at room temperature 24±0.5°C or otherwise mentioned. Chlorpromazine and reserpine were used as the standards.1. Gross observation : Groups of mice and rats (5 in each group), after an hour observation, were injected with graded doses of PCA9. Treated animals were observed for 5 hours for behavioral, neurological, autonomic and toxic manifestations according to the method outlined by Irwin (3). Gross effects of PCA9 were also studied in rabbits and dogs.2. Effect on body temperature : Rectal temperature of mice was recorded before and at 1/4, 1/2, 1, 2, 3, and 4 hours after the administration of the test compounds using

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“…It induces degenerative necrosis of the liver, pancreas, spleen, kidney, salivary gland, muscle, and myocardium in rats (Morrisey, Norred, Cole, & Dorner, 1985). It has also been associated with human poisoning (Rao & Husain, 1985), such as moldy corn toxicosis, known as "Kodua poisoning" (Bhide, 1962). This non-lethal disease in humans is characterized by sleeplessness, tremors, and giddiness (Rao & Husain, 1985).…”

Section: Sample Fungal Count (Cfu/g) Fungal Species Isolated 5°c 25°cmentioning

confidence: 99%

Toxigenic penicillia spoiling frozen chicken nuggets

Wigmann

Saccomori

Bernardi

et al. 2015

Food Research International

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Pharmacological Study and Fractionation of Paspalum Scrobiculatum Extract

Cited by 15 publications

References 7 publications

Forming Core Collections in Barnyard, Kodo, and Little Millets using Morphoagronomic Descriptors

Forming Core Collections in Barnyard, Kodo, and Little Millets using Morphoagronomic Descriptors

PHARMACOLOGICAL STUDY OF 1-(β-PHENYLETHYL) TRIAZOLO (4, 5-c) PYRIDINE HYDROCHLORIDE, A TRANQUILLIZING AGENT

Toxigenic penicillia spoiling frozen chicken nuggets

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