“…2 As a result, forskolin shows a broad range of physiological effects, including antihypertensive, 3 bronchospasmolytic, 4 neuroprotective, 5 and anticancer 6 activities, among others. 7 Forskolin has attracted considerable attention as a synthetic target due to both its therapeutic potential and to the synthetic challenge inherent to its densely functionalized skeleton (Scheme 1 ). In general, previous approaches to this molecule have utilized strategies whereby initial elaboration of the carbocyclic rings is followed by the late-stage introduction of the pyranone moiety.…”