Pharmacology of Contraceptive Steroids

Chatterton, J.

doi:10.3843/glowm.10386

Cited by 5 publications

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In animals and humans, the administration of a progestogen allows the female’s cyclicity to be manipulated, essentially to suppress oestrous cycles by inducing a prolonged anoestrus regardless of the stage of the reproductive cycle at the time of treatment. 2,3 In queens, long-acting drugs such as medroxyprogesterone acetate and proligestone are normally marketed as depot injections for oestrus postponement, while short-acting drugs such as megestrol acetate (which queens also respond well to when used long-term) are marketed as oral compounds for oestrus suppression.…”

Section: Progestogensmentioning

confidence: 99%

Reversible Control of Reproduction In Queens: Mastering the use of reproductive drugs to manipulate cyclicity

Romagnoli

Ferré-Dolcet²

2022

Journal of Feline Medicine and Surgery

View full text Add to dashboard Cite

Background: The literature is full of papers reporting side effects of progestogens in cats; however, they are, in fact, safe drugs, as discussed in this article. Gonadotropin-releasing hormone (GnRH) agonists and melatonin are additionally a practical solution for controlling cyclicity in queens, but they also have some contraindications and need to be used carefully. Clinical relevance: Mastering the use of reproductive drugs allows feline practitioners to handle many more clinical situations than can be solved using surgery. It is not necessary to be a specialist in reproduction to be able to halt cyclicity in a valuable breeding queen using hormones. Equipment and technical skills: A sound knowledge of appropriate dosages and criteria for patient selection for all reproductive drugs currently used in feline reproduction is the best guarantee of owner satisfaction and of ensuring the queen’s health. Availability of a serum progesterone assay, either in-house or via an external laboratory, is also important, in order to confirm a queen is at an appropriate stage of the reproductive cycle for treatment. Audience: This article is aimed principally (but not exclusively) at veterinarians working with cat breeders and whose clientele is increasingly interested in alternative methods of controlling reproduction in pet queens. Surgery is no longer the only choice, and practitioners who manage to keep abreast of new developments will be able to address clients’ needs in a modern, professional way. Evidence base: This review draws on a vast body of scientific evidence-based literature. Previously, personal (and sometimes misinformed) opinions, such as the proposed dangerous side effects of progestogens, have been perpetuated in the scientific literature. The papers cited in this review have therefore been carefully scrutinised to distinguish reliable information based on controlled studies from non-evidence-based information.

show abstract

Section: Progestogensmentioning

confidence: 99%