Pharmacology of Sedatives, Hypnotics, and Anxiolytics

Sloan, Jewell W.; Wala, Elzbieta P.

doi:10.1007/978-1-4757-2913-9_27

Cited by 2 publications

(1 citation statement)

References 119 publications

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“…1,[5][6][7] Prescription sedatives have a dose-response relationship effect on CNS activity: at higher doses, they have a CNS-depressant effect and can be used as hypnotics, whereas at lower doses, they produce an anxietyrelieving effect. [8][9][10] The number of sedative prescriptions may have increased as a result of different factors. These include the safety of newer agents (nonbenzodiazepine agents), the public's awareness of insomnia symptoms, and the sedative's expanded application in treating other mental health conditions.…”

Section: Introductionmentioning

confidence: 99%

The Effect of Veteran Status and Chronic Pain on Past 30-Day Sedative Use Among Community-Dwelling Adult Males

Otufowora,

Liu,

Okusanya

et al. 2024

J Am Board Fam Med

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Introduction: Given the high sedative prescription rate, the sedative-associated morbidity, and mortality nationally (especially among veterans), we aimed to test the hypothesis that veteran status in the presence of chronic pain would be associated with greater sedative use when compared with nonveteran status.Methods: The study participants were recruited by Community Health Workers (CHWs) through the ongoing community engagement program (HealthStreet) at the University of Florida. CHWs collected information on sociodemographic factors, health status, and past 30-day drug use patterns.Results: The study sample comprised 4,732 male participants, of which 21% were veterans, 58% were Blacks and 8.4% had used prescription sedatives in the past 30 days. Veterans (vs nonveterans) were twice as likely to have used prescription sedatives in the past 30 days in the presence of chronic pain.Conclusions: Veterans with chronic pain are a high-risk population for current prescription sedative use.

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