2020
DOI: 10.1177/1178633720943509
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Pharmacology, Phytochemistry, and Toxicity Profiles of Phytolacca dodecandra L’Hér: A Scoping Review

Abstract: Introduction: Phytolacca dodecandra L’Hér. is a native plant of sub-Saharan Africa and Madagascar which is traditionally used for various ailments. Concerned with the scope of the available evidence, we designed a scoping review to critically analyze scientific evidence on P dodecandra’s pharmacology, toxicity, and phytochemistry to validate its ethnomedical use. Methods: We searched without language restriction in MEDLINE, Google Scholar, Scopus, Embase, and Web of Science through December 2019. Both publishe… Show more

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Cited by 4 publications
(6 citation statements)
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References 42 publications
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“…It has been reported that the ethanol and hexane extracts of C. longa have significant antifungal activity against pathogenic fungi, such as Botrytis cinerea, Chaetomium olivaceum, Fusarium graminearum, and Mycogone perniciosa [ 70 , 71 ]. The methanol extract of its root had an antifungal effect against Candida albicans , Cryptococcus neoformans, Microsporum gypseum , and Trichophyton mentagrophytes [ 72 ]. Organic compound emitted from Trichoderma spp.…”
Section: Discussionmentioning
confidence: 99%
“…It has been reported that the ethanol and hexane extracts of C. longa have significant antifungal activity against pathogenic fungi, such as Botrytis cinerea, Chaetomium olivaceum, Fusarium graminearum, and Mycogone perniciosa [ 70 , 71 ]. The methanol extract of its root had an antifungal effect against Candida albicans , Cryptococcus neoformans, Microsporum gypseum , and Trichophyton mentagrophytes [ 72 ]. Organic compound emitted from Trichoderma spp.…”
Section: Discussionmentioning
confidence: 99%
“…However, previous studies have reported the use of R. tridentata in the treatment of helminths in livestock (Nalule et al 2011), strange traditional diseases (Gumisiriza et al 2020), and breast cancer (Dube et al, 2021) in Uganda. Though P. dodecandra has been reported to be traditionally used to treat dog bites/rabies in Ethiopia (Meresa et al 2017) and in DRC (Beressa et al 2020), this is the first time to be cited for the management of dog bites in Uganda. Other traditional uses in Uganda include; the management of skin disorders, inducing abortion, (Nakalembe et al 2019), and cleansing clothes (Beressa et al 2020).…”
Section: Medicinal Plant Species Used Traditionally To Manage Dog Bitementioning
confidence: 99%
“…Though P. dodecandra has been reported to be traditionally used to treat dog bites/rabies in Ethiopia (Meresa et al 2017) and in DRC (Beressa et al 2020), this is the first time to be cited for the management of dog bites in Uganda. Other traditional uses in Uganda include; the management of skin disorders, inducing abortion, (Nakalembe et al 2019), and cleansing clothes (Beressa et al 2020). In other parts of the world, P. dodecandra is used traditionally in treating malaria, sore throat, rabies, tuberculosis, asthma in DRC, epilepsy in Tanzania (Beressa et al 2020), gonorrhea, and helminthiasis in Ethiopia (Tahir, et al 2023).…”
Section: Medicinal Plant Species Used Traditionally To Manage Dog Bitementioning
confidence: 99%
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