Pharmacotherapeutic management of asthma in the elderly patient

Albertson, Timothy E; Pugashetti, Janelle Vu; Chau-Etchepare, F.; Chenoweth, James A.; Murin, Susan

doi:10.1080/14656566.2020.1795131

Cited by 6 publications

(4 citation statements)

References 185 publications

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“…The aims of asthma treatment in the AAP are the same as in young people: symptom control, reduction of exacerbations, minimizing adverse effects of the medication as well as the limitations in activities 18,70 . The key points are also the same as in the young individual, objective monitoring: avoiding triggering factors, pharmacological treatment, and patient education 54 .…”

Section: Treatmentmentioning

confidence: 99%

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Asthma in the Elderly: Systematic Approach to Improve the Prognosis

González-Barcala,

Calvo-Henriquez,

Martinez-Capoccioni

et al. 2023

BRN

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The objective of this review is to summarize the key points of asthma in elderly people including epidemiology, pathophysiology, clinical presentation and diagnosis and treatment. Although asthma was long considered a childhood disease, now it is clear that the disease is frequently diagnosed in adults over 65 years, with an incidence similar to that shown in other age groups. Furthermore, in advanced age population asthma is more severe, with more frequent exacerbations and higher mortality rate. From a pathophysiological point of view, two key processes are produced, immunosenescence and anatomical and mechanical changes with direct impact on lung function. The diagnosis should follow the same principles as the general population. However, underdiagnosis is frequent due to several factor such as comorbidities, poor perception of symptoms and reduction in physical activity. The treatment of these patients should pay particular attention to polypharmacy and multimorbidity.

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Section: Treatmentmentioning

confidence: 99%

“…The use of certain medications in the AAP may be dependent on the characteristics of these patients, such as physical and cognitive impairments, financial or daily life difficulties, comorbidities or multiple medication that may produce side effects, and different interactions 1,51,70 .…”

Section: Treatmentmentioning

confidence: 99%

Asthma in the Elderly: Systematic Approach to Improve the Prognosis

González-Barcala,

Calvo-Henriquez,

Martinez-Capoccioni

et al. 2023

BRN

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“…10,11 Inhaled, long-acting bronchodilators in combination with ICS are the standard treatment of ACO in the elderly patients. 12 Medication adherence to maintenance therapies in older adults with ACO may be suboptimal. Nili et al 13 reported that 56.7% of patients had persistently low adherence.…”

Section: Introductionmentioning

confidence: 99%

“… 10 , 11 Inhaled, long-acting bronchodilators in combination with ICS are the standard treatment of ACO in the elderly patients. 12 …”

Section: Introductionmentioning

confidence: 99%

Medication adherence in Medicare-enrolled older adults with asthma and chronic obstructive pulmonary disease before and during COVID-19 pandemic

Liu,

Silva Almodóvar,

Nahata

2023

Therapeutic Advances in Chronic Disease

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Background: Medication adherence in Medicare-enrolled older adults with asthma and chronic obstructive pulmonary disease (COPD) before and during the coronavirus disease 2019 (COVID-19) pandemic is unknown. Objectives: To evaluate medication adherence and determinants of high adherence before and during the COVID-19 pandemic in this population. Design: Retrospective cohort study. Methods: The proportion of days covered (PDC) reflected medication adherence from January to July 2019 and from January to July 2020. Patients <65 years of age, with COPD or asthma alone, or with cystic fibrosis were excluded. Paired t tests were used to assess adherence changes. Logistic regression explored association of age, sex, diagnosis of depression, number of medications, medication-related problems, prescribers, pharmacies, controller medication classes, albuterol rescue inhaler fills, oral corticosteroid fills, and having a 90-day supply with high adherence (PDC ⩾ 80%). Results: This analysis included 989 patients. In this cohort, 61.2% of patients received oral corticosteroids. Over 60% of patients had ⩾3 rescue fills in both 2019 and 2020. Medication adherence to controller medications significantly decreased for all controller medications ( p < 0.001) in 2020. In 2019 and 2020, number of controller medication classes and having a 90-day supply were associated with high adherence ( p < 0.001). In 2019, variables associated with high adherence also included number of medication-related problems and having ⩾3 albuterol rescue inhalers ( p < 0.001). Conclusion: Medication adherence to controllers significantly decreased during the pandemic among older adults with asthma and COPD. Patients with multiple controller classes and a 90-day supply were more likely to be highly adherent. A 90-day supply of medications should be used to facilitate access to medication during the pandemic. Healthcare professionals should assess medication adherence, resolve the barriers of adherence and medication-related problems to achieve desired clinical outcomes among older adults with both asthma and COPD.

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Asthme du sujet âgé : les spécificités du traitement

Perotin

2021

La Presse Médicale Formation

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Pharmacotherapeutic management of asthma in the elderly patient

Cited by 6 publications

References 185 publications

Asthma in the Elderly: Systematic Approach to Improve the Prognosis

Asthma in the Elderly: Systematic Approach to Improve the Prognosis

Medication adherence in Medicare-enrolled older adults with asthma and chronic obstructive pulmonary disease before and during COVID-19 pandemic

Asthme du sujet âgé : les spécificités du traitement

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