Handbook of Pain Relief in Older Adults 2004
DOI: 10.1007/978-1-59259-668-3_6
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Pharmacotherapy of Pain in Older Adults

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“…However, opioid medications are associated with increased risk factors, including confusion, sedation, delirium, nausea, and intestinal obstruction 14–18 . In addition, numerous studies have indicated that the geriatric population is at a significantly higher risk for adverse events or side effects from opioid medications 8,13,14,16,17,19–25 . The geriatric population is more likely to experience adverse drug events due to age‐related changes in pharmacokinetics, drug‐drug interactions due to an increased reliance on polypharmacy, drug‐disease interactions, and increased sensitivity to drug side effects, including sedation and cognitive changes 13,14,17,19–21,26,27 .…”
Section: Introductionmentioning
confidence: 99%
“…However, opioid medications are associated with increased risk factors, including confusion, sedation, delirium, nausea, and intestinal obstruction 14–18 . In addition, numerous studies have indicated that the geriatric population is at a significantly higher risk for adverse events or side effects from opioid medications 8,13,14,16,17,19–25 . The geriatric population is more likely to experience adverse drug events due to age‐related changes in pharmacokinetics, drug‐drug interactions due to an increased reliance on polypharmacy, drug‐disease interactions, and increased sensitivity to drug side effects, including sedation and cognitive changes 13,14,17,19–21,26,27 .…”
Section: Introductionmentioning
confidence: 99%