Pharmacovigilance education to healthcare professionals: Will it affect their performance in reporting adverse drug reactions?

Abstract

Pharmacovigilance (PV) is essential for the detection and prevention of adverse drug reactions (ADRs). According to the World Health Organization (WHO), PV is defined as ''the science and activities relating to the detection, assessment, understanding and prevention of adverse effects or any other drug-related problem". 1 The WHO defines ADR as "a response to a drug which is noxious and unintended, and which occurs at doses normally used in man for the prophylaxis, diagnosis or therapy of disease, or for the modifications of physiological function". 2 They are one of the leading causes of morbidity and mortality around the world resulting in increased healthcare costs. 3,4 The WHO stated that ADRs were responsible for a significant number of hospital admission ranging from 0.3% to 11%. 2 In addition, a meta-analysis has shown that ADRs were considered from the 4 th to the 6 th most common causes of death. 5 Recently, PV is of great importance as it represents a key element in the regulation of effective drug use systems in clinical practice. 6 The main goal of PV is to minimise harm caused by medications through rationalising their use, and to protect and promote

Knowledge, attitude and practice of hospital pharmacists towards pharmacovigilance and adverse drug reaction reporting in Najran, Saudi Arabia

“…The participants who had received training had a significantly better-answered definition of PV (P = 0.00) and reported ADRs (P = 0.00) compared to those without training, similar to the findings of other studies ( Gupta et al, 2015 ). Several studies have established the benefits of regular training and educational interventions on KAP, including actual reporting ( Ahmad et al, 2013 , Hanafi et al, 2014 , Abu Farha et al, 2018 , Ibrahim et al, 2021 ).…”

“…There is a strong relationship between ADR reporting and healthcare professionals' knowledge, attitude, and practice (KAP) ( Ibrahim et al, 2021 ). Studies have demonstrated that streamlining KAP concerning PV is vital in detailing methodologies to encourage ADR reporting.…”

Knowledge of pharmacovigilance among healthcare professionals and the impact of an educational intervention

“…This is in agreement with a study done by Ganesan et al in a tertiary care centre in South India, in which the knowledge, attitude and practice of both doctors and nurses improved following an educational intervention [ 5 ]. A study on pharmacovigilance knowledge, attitude, and practice among doctors, nurses, and pharmacists in an Egyptian hospital showed low baseline scores which improved significantly following an educational intervention by clinical pharmacists from the pharmacovigilance centre [ 12 ]. In an interventional study of healthcare professionals from six teaching hospitals in Nigeria, the intervention group attended a seminar followed by monthly reinforcements via text messages for one year.…”

Barriers and facilitators to pharmacovigilance activities in Pakistan: A healthcare professionals-based survey

“…among HCPs from Egypt, Nigeria, India, Nepal, and Pakistan, where an improvement in the knowledge, attitude, and practices were observed following an educational intervention promoting ADR reporting [34][35][36][37][38]. Lack of time to report an ADR was highlighted as an important barrier by the majority of the HCPs.…”