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Dental infections, which include anything from severe periodontal illnesses and abscess forms to routine tooth caries, are a major public health risk. This review article focuses on the pathophysiology and treatment of dental infections. A narrative review was conducted based on several published articles, relevant journals, and books in Google Scholar PubMed using the keywords dental caries, periodontal disease, gingivitis, and related diseases; we excluded duplicated information. Our review illustrated the types of dental infections and the proper antimicrobial drug that is suitable for this disease. Drawing from recent research findings and clinical evidence, we explore the spectrum of bacteria commonly associated with dental infections and their susceptibility profiles to various antibiotics. Emphasis is placed on understanding the mechanisms of antibiotic action and resistance in the context of dental pathogens, shedding light on optimal treatment regimens and potential challenges in clinical management. Additionally, we go over the clinical consequences of antibiotic therapy in dentistry, taking into account factors like patient selection, dose guidelines, and side effects. The management of dental infections through antimicrobial strategies has undergone significant advancements, as evidenced by this updated review. Besides the normal methods, emerging technologies such as 3D printing for drug delivery of antibiotics and disinfectants hold promise in enhancing treatment efficacy and patient outcomes. By leveraging the precision and customization afforded by 3D printing, dentistry can tailor antimicrobial interventions to individual patient needs, optimizing therapeutic outcomes while minimizing adverse effects.
Dental infections, which include anything from severe periodontal illnesses and abscess forms to routine tooth caries, are a major public health risk. This review article focuses on the pathophysiology and treatment of dental infections. A narrative review was conducted based on several published articles, relevant journals, and books in Google Scholar PubMed using the keywords dental caries, periodontal disease, gingivitis, and related diseases; we excluded duplicated information. Our review illustrated the types of dental infections and the proper antimicrobial drug that is suitable for this disease. Drawing from recent research findings and clinical evidence, we explore the spectrum of bacteria commonly associated with dental infections and their susceptibility profiles to various antibiotics. Emphasis is placed on understanding the mechanisms of antibiotic action and resistance in the context of dental pathogens, shedding light on optimal treatment regimens and potential challenges in clinical management. Additionally, we go over the clinical consequences of antibiotic therapy in dentistry, taking into account factors like patient selection, dose guidelines, and side effects. The management of dental infections through antimicrobial strategies has undergone significant advancements, as evidenced by this updated review. Besides the normal methods, emerging technologies such as 3D printing for drug delivery of antibiotics and disinfectants hold promise in enhancing treatment efficacy and patient outcomes. By leveraging the precision and customization afforded by 3D printing, dentistry can tailor antimicrobial interventions to individual patient needs, optimizing therapeutic outcomes while minimizing adverse effects.
BACKGROUND: The presence of acute pain is a serious condition, perhaps, the most terrible negative feeling of a person. Therefore, it is advisable to intraoperatively use means of acute pain control for comfort and to prevent the formation of chronic pain syndrome. Using a multimodal approach to acute pain management allows for better outcomes. The more we engage antinociceptive receptors to control pain, the more comfortable our patient feels. Alpha-2-adrenergic agonists clonidine became an important part of the anesthesiologist's set in the perioperative period. It is the selective effect of dexmedetomidine on alpha-2a central and peripheral receptors and alpha-2c receptors that made it possible to use the drug more widely during procedural sedation. The joint use of several drugs for procedural sedation is aimed at obtaining the maximum possible comfort for the patient, the attending physician, and the anesthesiology team, reducing the medication load and awakening as soon as possible. Gaining practical experience in using certain combinations of drugs and analyzing useful negative effects helps to balance and satisfy all needs. PERSONAL EXPERIENCE. Two clinical cases with a typical development but differing in surgical load are presented, describing the effects associated with the use of Precedex (dexmedetomidine hydrochloride) in the introduction of procedural sedation in ambulatory dentistry. CONCLUSIONS. The use of clonidine or dexmedetomidine (Precedex) intraoperatively together with propofol during procedural sedation in ambulatory dentistry allows reliable control of pain in the perioperative period when basic traditional drugs (acetaminophen, NSAIDs) are used in safe doses, reduces the maintenance dose of propofol during the procedure, prevents the vomiting reflex, provides the possibility of comfortable execution of the doctor's commands (surgeon, implantologist, orthopedics) and faster transfer of the patient to the recovery room.
BACKGROUND: The presence of acute pain is a serious condition, perhaps, the most terrible negative feeling of a person. Therefore, it is advisable to intraoperatively use means of acute pain control for comfort and to prevent the formation of chronic pain syndrome. Using a multimodal approach to acute pain management allows for better outcomes. The more we engage antinociceptive receptors to control pain, the more comfortable our patient feels. Alpha-2-adrenergic agonists clonidine became an important part of the anesthesiologist's set in the perioperative period. It is the selective effect of dexmedetomidine on alpha-2a central and peripheral receptors and alpha-2c receptors that made it possible to use the drug more widely during procedural sedation. The joint use of several drugs for procedural sedation is aimed at obtaining the maximum possible comfort for the patient, the attending physician, and the anesthesiology team, reducing the medication load and awakening as soon as possible. Gaining practical experience in using certain combinations of drugs and analyzing useful negative effects helps to balance and satisfy all needs. PERSONAL EXPERIENCE. Two clinical cases with a typical development but differing in surgical load are presented, describing the effects associated with the use of Precedex (dexmedetomidine hydrochloride) in the introduction of procedural sedation in ambulatory dentistry. CONCLUSIONS. The use of clonidine or dexmedetomidine (Precedex) intraoperatively together with propofol during procedural sedation in ambulatory dentistry allows reliable control of pain in the perioperative period when basic traditional drugs (acetaminophen, NSAIDs) are used in safe doses, reduces the maintenance dose of propofol during the procedure, prevents the vomiting reflex, provides the possibility of comfortable execution of the doctor's commands (surgeon, implantologist, orthopedics) and faster transfer of the patient to the recovery room.
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