BACKGROUND
Addressing record high rates of Chlamydia trachomatis (Ct) incidence in the United States (U.S.) requires the utilization of effective strategies, such as expedited partner therapy (EPT), to reduce reinfection and further transmission. EPT, which can be given as a prescription or medication, is a strategy to treat the sexual partners of index patients diagnosed with a sexually transmitted infection (STI) without prior medical evaluation of the partners.
OBJECTIVE
There are multiple steps in the prescription-EPT cascade and we sought to identify pharmacy-level barriers to implementing prescription-EPT for Ct treatment.
STUDY DESIGN
We used spatial analysis and ArcGIS, a geographic information system, to map and assess geospatial access to pharmacies within Baltimore, Maryland neighborhoods with the highest rates of Ct (1180.25-4255.31 per 100,000 persons). EPT knowledge and practices were collected via a telephone survey of pharmacists employed at retail pharmacies located in these same neighborhoods. Cost of antibiotic medication in U.S. Dollars (USD) was collected.
RESULTS
Census tracts with the highest Ct incidence rates had lower median pharmacy density than other census tracts (26.9 per 100,000 v. 31.4 per 100,000, P<.001). We identified 25 pharmacy deserts. Areas defined as pharmacy deserts had larger proportions of Black and Hispanic or Latino populations compared to non-Hispanic whites (93.1% v. 6.3%, P<.001) and trended toward higher median Ct incidence rates (1170.0 per 100,000 v. 1094.5 per 100,000, P=.110) than non-pharmacy desert areas. Of the 52 pharmacies identified, 96% (50/52) responded to our survey. Less than a fifth of pharmacists (18%, 9/50) were aware of EPT for Ct. Most pharmacists (59%, 27/46) confirmed they would fill an EPT prescription. The cost of a single dose of azithromycin (1 gram) ranged from 5-39.99 USD (median, 30 USD).
CONCLUSION
Limited geographic access to pharmacies, lack of pharmacist awareness of EPT, and wide variation in EPT medication cost are potential barriers to implementing prescription-EPT. Although most Baltimore pharmacists were unaware of EPT, they were generally receptive to learning about and filling EPT prescriptions. This finding suggests the need for wide dissemination of educational material targeted to pharmacists. In areas with limited geographic access to pharmacies, EPT strategies that do not depend on partners physically accessing a pharmacy merit consideration.