Pharmakologie der Narkose

The Effect of Ethanol on the Gastrointestinal Absorption of Drugs in the Rat

“…In recent years the ethanol-drug interactions have become a more and more serious problem, not only because of the increased and often indiscriminate use of central depressant drugs, but also because of the increased demand for unimpaired coordination and judgment, required for the safe operation of automobiles and other complex machinery. Under the direction of Professor K. SOEHRING, the Deutsche Gesellschaft fur Verkehrsmedizin has had annual meetings in Bad Oeynhausen since 1960, dealing particularly with this topic (SOEHRING 1960). Pharmacodynamic interactions between ethanol and drugs have been investigated both experimentally and clinically, though, there is still some controversy about the nature of the observed synergism.…”