The Ti-6Al-4V alloy is an important aviation material, but has a poor resistance to slide wear. Laser cladding of the Al 3 Ti + Ni/ Cr/C + TiB 2 /Al 2 O 3 + SiC/nano-CeO 2 preplaced powders on the Ti-6Al-4V alloy can form the Ti 3 Al/g-Ni matrix composite coating, which improves the wear resistance of the substrate. In this study, the Al 3 Ti + Ni/Cr/C + TiB 2 /Al 2 O 3 + SiC/nano-CeO 2 lasercladded coating was researched by means of X-ray diffraction, scanning electron microscopy, and energy dispersive spectrometry. The experimental results indicate that under the action of SiC/nano-CeO 2 , this composite coating exhibited a fine microstructure. Furthermore, the proper content of nano-CeO 2 decreased the crack tendency. The results above indicated that, it is feasible to improve the tribological property of the Al 3 Ti + Ni/Cr/C + TiB 2 /Al 2 O 3 laser-cladded coating by adding of SiC/nano-CeO 2 .