For isolated vacancies in ordered local-moment antiferromagnets we show that the magnetic-field linear-response limit is generically singular: The magnetic moment associated with a vacancy in zero field is different from that in a finite field h in the limit h → 0 + . The origin is a universal and singular screening cloud, which moreover leads to perfect screening as h → 0 + for magnets which display spin-flop bulk states in the weak-field limit.Defects are ubiquitous in solids. In magnets with localized spin moments, typical classes of defects are missing or extra spins, arising, e.g., from substitutional disorder. Very often, even small concentrations of such defects produce a large magnetic response at low temperatures: Quasi-free spins cause a Curie tail in the magnetic susceptibility, which then is routinely subtracted from raw experimental data. Assuming independent defects, the amplitude of the Curie tail can be utilized to estimate the defect concentration, provided that the behavior of a single defect is known.Here we discuss the physics of isolated vacancies in antiferromagnets (AF) which display semiclassical longrange order (LRO) in the ground state [1]. In zero magnetic field, the state with a single vacancy has a finite uniform magnetic moment, m 0 , because the vacancy breaks the balance between the sublattices. For collinear magnets, m 0 is quantized to the bulk spin value, m 0 = S [2, 3], while in the non-collinear case fractional values of m 0 occur due to the local relief of frustration [4]. These vacancy moments are expected to show up in magnetization measurements, and they produce a low-temperature Curie contribution to the uniform susceptibility in the two-dimensional (2d) case where bulk order is prohibited by the Mermin-Wagner theorem [3][4][5][6][7].In this paper we show that, in an applied field h, nontrivial screening of the vacancy moment occurs, such that the linear-response limit h → 0 + is singular for a magnet with a single vacancy, Fig. 1: The vacancy-induced magnetization jumps discontinuously from its zero-field value m 0 to a different value m(h → 0 + ) upon applying an infinitesimal field h. Thus, measurements of the vacancy-induced moment m(h) in a finite field h cannot detect the zero-field value m 0 even for small h [8], which is of obvious relevance for any experiment trying to quantify the defect contribution to a sample's magnetization or susceptibility. Furthermore, the spin texture around the vacancy at finite h has a piece [9] which is singular as h → 0 + -in a sense made precise belowwhich screens the vacancy-induced moment perpendicular to h. For magnets which feature spin-flop states (with all spins perpendicular to h as h → 0 + ) in the absence of the vacancy, this leads to a semiclassical version of perfect screening of the vacancy moment, m(h → 0 + ) = 0.In the body of paper, we present general arguments and microscopic calculations supporting these claims. Explicit results will be given in a 1/S expansion for spin-S AFs on 2d lattices, with(1) but our results...