Phase II studies using electroporation therapy in patients with recurrent head and neck cancer: a safe and active treatment approach

Goldfarb, P. M.; Hill, Fiona H.

doi:10.1016/s0959-8049(99)81079-x

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“…Lastly, a recent cross‐institutional collaborative study was presented in which intralesional bleomycin with and without concomitant electroporation was used. 20 In trial no. 1, intralesional bleomycin was used alone, and it did not have any complete or even partial responses (0 of 32 lesions).…”

Section: Discussionmentioning

confidence: 99%

Electroporation Therapy for Head and Neck Cancer Including Carotid Artery Involvement

Allegretti

Panje

2001

The Laryngoscope

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We found EPT to be safe and efficacious in patients with head and neck cancer, even with internal carotid artery involvement. Patients with early stage recurrences have the potential for prolonged survival beyond 2 years without the morbidity of surgery and radiation or toxicity of systemic chemotherapy. Because of its superb access qualities even for bulky tumors, EPT is a potential method of delivery for other tumoricidal agents such as in genetic-altering schemes.

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Section: Discussionmentioning

confidence: 99%