“…Characterized by good water solubility, broad anti-tumor spectrum, strong anti-tumor activity, no achiasmate drug resistance with other platinum-based drugs and low toxicity, it exerts definite effects in the treatment of various tumors, such as breast cancer (Engel et al, 2012;Deng et al, 2013), lung cancer (Xie et al, 2012), esophageal carcinoma, gastrointestinal cancer and malignant pleural effusion and ascites. In terms of primary hepatic carcinoma, the in-vitro experimental studies have demonstrated that LBP has an inhibitory effect on hepatocellular carcinoma cells, and can be recommended to treat primary hepatic carcinoma in clinic (Qian et al, 2009;Wu et al, 2010;Wang et al, 2012).…”