Phase-sensitive surface plasmon resonance sensors for highly sensitive bioanalysis

Wang, Peng

doi:10.1016/bs.coac.2021.09.001

Cited by 2 publications

(1 citation statement)

References 105 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Traditional spectroscopic techniques relying solely on intensity or wavelength interrogation have proven inadequate in addressing this issue. A promising solution is found in phase interrogation mode, as demonstrated by pioneering studies showing significantly improved sensitivity compared to amplitude detection. − …”

Section: Introductionmentioning

confidence: 99%

Phase Singularity in Random Gold Metasurface for Refractive Index Sensing: Experimental Demonstration and Theoretical Analysis

Cuanalo-Fernández,

Korneev,

Cosme

et al. 2024

J. Phys. Chem. C

View full text Add to dashboard Cite

This study delves into the phenomenon of near-zero reflectance and phase singularity within a random array of gold nanoislands, employing a combination of theoretical and experimental approaches. The nanoislands are fabricated through the thermal dewetting of ultrathin gold films deposited via magnetron sputtering onto a glass substrate. Their morphology is characterized using scanning electron microscopy and atomic force microscopy. To unravel the plasmonic behavior, we conducted measurements of reflectance and phase spectra using a common-path interferometer in an attenuated total reflectance configuration. Our analysis reveals a partial state of topological darkness in the examined sample, characterized by near-zero reflection for the p polarization component. This discovery is further substantiated by the observation of phase singularity, as evidenced by abrupt ±π phase jumps in the differential phase spectra. Moreover, our study demonstrates the utility of measuring the phase and its derivative at resonance near the singularity for highly sensitive detection of changes in the bulk refractive index of the surrounding medium. The experimental findings are rigorously validated by comparing them with analytically calculated reflectance and phase spectra using the island film theory, yielding a good agreement.

show abstract

Section: Introductionmentioning

confidence: 99%

Phase Singularity in Random Gold Metasurface for Refractive Index Sensing: Experimental Demonstration and Theoretical Analysis

Cuanalo-Fernández,

Korneev,

Cosme

et al. 2024

J. Phys. Chem. C

View full text Add to dashboard Cite

show abstract

Graphene-based Nanocomposites for Cholesterol Detection

An’amt,

Mohd Zin,

Sajab

et al. 2023

Graphene-Based Nanocomposite Sensors

View full text Add to dashboard Cite

Great progress has been made in the development of graphene-based nanocomposites as sensing materials for cholesterol detection using various sensing techniques such as electrochemical, fluorescence, colorimetric, surface plasmon resonance (SPR), surface-enhanced Raman spectroscopy (SERS), and field-effect transistor (FET) sensors. This chapter focuses on the unique properties of graphene that make it an ideal material for sensing applications and summarizes the recent advances in the synthesis and characterization of graphene-based nanocomposites for cholesterol sensing. The various sensing techniques used for cholesterol detection are compared and contrasted, highlighting their strengths and limitations. The potential of graphene-based nanocomposites for cholesterol sensing in various applications is discussed, including biomedical and environmental monitoring. The innovative use of graphene-based nanocomposite sensors and the focus on multi-biomarker detection described in this chapter indicate a significant breakthrough in the field of medical diagnosis and sensing.

show abstract

Phase-sensitive surface plasmon resonance sensors for highly sensitive bioanalysis

Cited by 2 publications

References 105 publications

Phase Singularity in Random Gold Metasurface for Refractive Index Sensing: Experimental Demonstration and Theoretical Analysis

Phase Singularity in Random Gold Metasurface for Refractive Index Sensing: Experimental Demonstration and Theoretical Analysis

Graphene-based Nanocomposites for Cholesterol Detection

Contact Info

Product

Resources

About