Encyclopedia of Biocolloid and Biointerface Science 2V Set 2016
DOI: 10.1002/9781119075691.ch69
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Phase Separation Phenomena in Drug Systems

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“…The CAinduced depression of CP was expected because this effect has already been reported for polar organic compounds such as alkyl parabens or alkanols in C 12 E 6 solutions and Triton X-100. 39,51,52 Preferential solubilization of the hydrophobic compound into the surfactant aggregates could explain this effect because it leads first to a micellar growth and change of shape and, as a consequence, to a decrease of the CP. 39,51 As for C 12 E 4 , the aqueous solution at 25 °C is very viscous because of the formation of liquid crystals.…”
Section: Resultsmentioning
confidence: 99%
“…The CAinduced depression of CP was expected because this effect has already been reported for polar organic compounds such as alkyl parabens or alkanols in C 12 E 6 solutions and Triton X-100. 39,51,52 Preferential solubilization of the hydrophobic compound into the surfactant aggregates could explain this effect because it leads first to a micellar growth and change of shape and, as a consequence, to a decrease of the CP. 39,51 As for C 12 E 4 , the aqueous solution at 25 °C is very viscous because of the formation of liquid crystals.…”
Section: Resultsmentioning
confidence: 99%
“…The anionic surfactants include perfluoroalkyl surfactant LFOS, which shows an antagonistic interaction with surfactants bearing alkyl groups, resulting in a positive β value. For the Gemini surfactants [39] and bile salts [40], reviews on the interaction parameter β have recently been reported. Some compounds were excluded due to their undefined structure [41].…”
Section: Resultsmentioning
confidence: 99%