Phenolic composition and bioactivities of sea buckthorn (Hippophae rhamnoides L.) fruit and seeds: an unconventional source of natural antioxidants in North America

Abstract

BackgroundSea buckthorn (Hippophae rhamnoids L.) was introduced in Canada in the early 2000s. This plant bears fruits with high commercial value in other countries due to its premium oil. Nevertheless, sea buckthorn berries are also a rich source of bioactives with nutraceutical potential, especially the variety grown in Newfoundland (Canada), which has not previously been characterized. As such, this study evaluated the composition of polyphenols in sea buckthorn pomace and seeds, as well as their prospective health‐promoting effects.ResultsPolyphenolic identification by HPLC‐UV‐MS‐TOF revealed the presence of 24 compounds in the seeds and 16 compounds in the pomace, including phenolic acids, flavonoids, and tannins, with ellagic acid derivative IV (pomace, 52.13 μg/g) and (+)‐catechin (seeds, 690.8 μg/g) being the most dominant. Sea buckthorn extracts displayed in vitro antidiabetic and anti‐obesity potential by inhibiting α‐glucosidase (71.52‐99.31%) and pancreatic lipase (15.80‐35.61%) enzymes, respectively. The extracts also protected LDL‐cholesterol (50.97‐89.67%) and supercoiled DNA (35.11‐79.84%) from oxidative damage.ConclusionSea buckthorn berries grown in Canada showed promising health benefits induced by their rich and diverse polyphenolic profile and need to be considered for further commercial expansion as a bioactive‐loaded superfruit.This article is protected by copyright. All rights reserved.