Phenolic Constituents, Antioxidant and Preliminary Antimycoplasmic Activities of Leaf Skin and Flowers of  Aloe vera (L.) Burm. f. (syn. A. barbadensis Mill.) from  the Canary Islands (Spain)

López, Aroa; Tangil, de; Vega-Orellana, Orestes M.; As, Ramírez; Rico, Milagros

doi:10.3390/molecules18054942

Cited by 103 publications

(81 citation statements)

References 39 publications

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“…Owing to the rich chemical composition, as well as its antioxidative properties, aloe has become the focus of numerous phytochemical and pharmacological tests which deliver very interesting results (Cieślik and Turcza, 2015;Khanam and Sharma, 2015;López et al, 2013;Nowak and Starek, 2003). It has been proved it supports the treatment of gastrointestinal canal diseases, such as: inflammations, stomach, large intestine and duodenum ulcers.…”

Section: Introductionmentioning

confidence: 99%

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Antioxidant activity of true aloe (Aloe vera) extract in model systems

Hęś¹,

Dziedzic²,

Thanh-Blicharz³

et al. 2016

Nauka Przyr. Technol.

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SummaryBackground. Aloe contains numerous bioactive compounds which are attributed to have health advantages. Widely used in the cosmetic and pharmaceutical industries, also found its application in the food industry. The antioxidant compounds in aloe may increase the stability and nutritional value of food. The aim of the paper was to evaluate the results of the antioxidant properties of aqueous extract of aloe in model systems. Material and methods. Analyses were conducted on true aloe (Aloe vera L.). Extraction was run using water at temperature 80-90°C. The level of phenolics was determined spectrophotometrically with the Folin-Ciocalteu reagent, using gallic acid as a standard. Antioxidant activity of extract was analysed in relation to linoleic acid, running incubation for 19 h, by scavenging of stable radical DPPH (2,2-diphenyl-1-picrylhydrazyl) and cation radical ABTS (2,2'-azino-bis[3--ethylbenzothiazoline-6-sulfonic acid]) and on the basis of metal chelating ability. Recorded results were compared with the activity of BHT (butylated hydroxytoluene). Results. The total phenolic content of water extract of aloe was 17.85 mg/g d.m. The extract exhibited concentration-dependent DPPH and ABTS radical scavenging activity. The ability was in the range of 4.32-8.87 and 0.58-0.87 mg of trolox per 1 g d.m., respectively. A lower chelating ability of the aloe extract was 1.23 mg EDTA per 1 g d.m. at 20 mg/ml concentration and the higher was 8.76 mg EDTA per 1 g d.m. at 10 mg/ml concentration. The aloe extract reduced levels of the conjugated dienes in the emulsion system. The samples with additions of 0.1-0.5 mg/ml extract contain over 90% less of dienes than control sample. The addition of 0.05 mg/ml and 0.06 mg/ml results in significantly lower (40% and 57%, respectively) activities of the aloe extract.Hęś, M., Dziedzic, K., Le Thanh-Blicharz, J., Kmiecik, D., Górecka, D. (2016). Antioxidant activity of true aloe (Aloe vera) extract in model systems. Nauka Przyr. Technol., 10, 4, #53. DOI: http://dx.doi.org/10.17306/J. NPT.2016.4.53 2 Conclusions. The extract of aloe showed different antioxidant properties in various model systems. The available literature on the antioxidant potential of aloe is still rather scarce. Due to the complex composition and broad activity of aloe, raw material should be further studied.

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Section: Introductionmentioning

confidence: 99%

“…The content of polyphenolic compounds is slightly higher in the leaf skin than in the flower. Catechin prevails in the skin, while the flower contains more gentisic acid (López et al, 2013).…”

Section: Introductionmentioning

confidence: 99%

Antioxidant activity of true aloe (Aloe vera) extract in model systems

Hęś¹,

Dziedzic²,

Thanh-Blicharz³

et al. 2016

Nauka Przyr. Technol.

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“…This plant is commonly used in folk medicine as it is antibacterial, antioxidant, antidiabetic, anticarcinogenic, hypocholesterolemic, hepatoprotective, and nephroprotective [12][13][14][15][16][17]. The polyphenolics and flavonoids reported so far in the aloe skin include sinapic acid, quercitrin, kaempferol, apigenin, catechin, quercetin, epicatechin, syringic acid, chlorogenic acid, gentisic acid, caffeic acid, ferulic acid, rutin, miricetin, and vanillic acid [18]. The possible protective activity of Aloe barbadensis aqueous extract against Cd-induced renal and hepatotoxicity has not been reported so far.…”

Section: Introductionmentioning

confidence: 99%

Investigating the Ameliorative Potential of the Aloe barbadensis Aqueous Fraction on Oxidative Stress Markers and Biochemical Parameters in Cadmium-Intoxicated Rabbits

Hussain

Chaudhry

Anjum

et al. 2016

Pol. J. Environ. Stud.

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This study was conducted to evaluate the possible protective effects of the flavonoid-rich fraction of Aloe barbadensis leaf skin on cadmium (Cd)-induced toxicity in male albino rabbits. Cadmium is a notable environmental pollutant due to its wider range of toxic manifestations. The aqueous fraction of aloe extract (AAF) showed higher phenolics, flavonoids, and antioxidant capacity among other fractions, suggesting its rationale use in this study. Twenty-four rabbits were randomly divided into four groups, including the control group (receiving only vehicle), the Cd group (receiving Cd, 5.1 mg/kg/day), the AAF groups (receiving AAF, 200 mg/Kg/day), and the Cd+AAF group (receiving the same concentrations as the Cd and AAF groups). Oral treatment over a period of 40 days significantly increased (p<0.05) biochemical marker enzymes, including transaminases (AST, ALT), alkaline phosphatase, γ-glutamyl transferase, creatinine, and urea, while total bilirubin (Tb) and albumin were decreased on days 10, 20, 30, and 40 in the Cd group as compared to control. A significant decrease (p<0.05) in enzyme levels and increases in Tb and albumin for Cd+AAF were observed as compared to Cd-treated rabbits. Contents of superoxide dismutase, catalase, and vitamins C and E in liver and kidney tissues were significantly increased (p<0.05), while cadmium content was significantly decreased (p<0.05) for Cd+AAF rabbits as compared to Cd-intoxicated rabbits. Values of all the parameters in only the AAF group were near to control. The histopathological studies for liver and kidney have also supported the Cd+AAF group markedly reducing the toxicity of Cd in both tissues to near normal. Thus, the results suggest that the flavonoid-rich fraction of AAF may

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“…Flavonoids exert antioxidant activity by acting as free radical scavengers through the donation of a hydrogen atom [19] . This property is attributed to the phenolic hydroxyl groups attached to the ring moiety.…”

Section: Discussionmentioning

confidence: 99%

Anti-obesity and antioxidant activity of dietary flavonoids from Dioscorea steriscus tubers

2014

JCLM

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Phenolic Constituents, Antioxidant and Preliminary Antimycoplasmic Activities of Leaf Skin and Flowers of Aloe vera (L.) Burm. f. (syn. A. barbadensis Mill.) from the Canary Islands (Spain)

Cited by 103 publications

References 39 publications

Antioxidant activity of true aloe (Aloe vera) extract in model systems

Antioxidant activity of true aloe (Aloe vera) extract in model systems

Investigating the Ameliorative Potential of the Aloe barbadensis Aqueous Fraction on Oxidative Stress Markers and Biochemical Parameters in Cadmium-Intoxicated Rabbits

Anti-obesity and antioxidant activity of dietary flavonoids from Dioscorea steriscus tubers

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