Phenolic contents, composition and antioxidant activity of essential oils obtained from Iranian populations of Apium graveolens, and their canonical correlation with environmental factors

Salimi, Fatemeh; Fattahi, Mohammad; Hamzei, J.

doi:10.1016/j.bse.2022.104394

Cited by 5 publications

(9 citation statements)

References 22 publications

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“…For example, correlation values between total phenolic content and CUPRAC, metal chelate, and phosphomolybdenum were greater than 0.8. Consistent with our findings, several researchers reported a positive correlation between the total phenolic amounts and antioxidant properties [54,55] . With regard to enzyme inhibitory properties, three enzymes were correlated with the total phenolic contents in the extracts.…”

Section: Resultssupporting

confidence: 92%

“…Another study showed the link between antioxidant intake and reduced symptoms of dementia [62] . In the present study, the Multivariate Analysis clearly established a direct relationship between antioxidant potential and phenolic contents of CA−C and CA−H, which is supported by several research reports [54,55] . Further, AChE, BChE and amylase inhibitory activity was also correlated with the total phenolic contents in the extracts.…”

Section: Discussionsupporting

confidence: 88%

“…[62] In the present study, the Multivariate Analysis clearly established a direct relationship between antioxidant potential and phenolic contents of CAÀ C and CAÀ H, which is supported by several research reports. [54,55] Further, AChE, BChE and amylase inhibitory activity was also correlated with the total phenolic contents in the extracts. Since medicinal plants with antioxidant activities also exhibit potential for AD treatment, it can be concluded that in addition to play a competitive role in nutraceutical products, the extract(s) of C. arvensis can also strong candidate for the medicinal formulations to prevent neurodegenerative diseases.…”

Section: Discussionmentioning

confidence: 87%

“…Consistent with our findings, several researchers reported a positive correlation between the total phenolic amounts and antioxidant properties. [54,55] With regard to enzyme inhibitory properties, three enzymes were correlated with the total phenolic contents in the extracts. The enzymes were AChE (R: 0.72), BChE (0.83) and amylase (R: 0.93).…”

Section: Multivariate Analysismentioning

confidence: 99%

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Total Bioactive Contents, Metabolic Profiling, Docking Studies, Antioxidant and Enzyme Inhibition Activities of Convolvulus Arvensis L. and Multivariate Analysis to Unravel a Potential Herb as Natural Resource for Pharmaceutical Industry

Tousif

Nazir

Saleem

et al. 2022

Chemistry & Biodiversity

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Convolvulus arvensis L. is an evergreen herb growing in various regions of Pakistan. Despite of several medicinal properties associated to this herb, it was not investigated scientifically for its bioactive compounds and detailed pharmaceutical properties. Therefore, its methanolic extract was divided into hexane (CAÀ H), chloroform (CAÀ C), ethyl acetate (CAÀ E) and butanol (CAÀ B) soluble fractions. CAÀ H and CAÀ C were found rich in phenolics (30.73 � 0.63 and 20.15 � 0.59 mg GAE/g of the extract, respectively), and the same fractions exhibited significant antioxidant activities (DPPH: 5.23 � 0.11 & 12.34 � 0.17 mg TE/g extract, respectively; ABTS: 36.82 � 0.04 & 56.74 � 0.61 mg TE/g extract, respectively). Also in CUPRAC activity assay, CAÀ H and CAÀ C exhibited highest activities as 87.30 � 0.46 and 56.74 � 0.61 mg TE/g extract, respectively, while CAÀ C was most active in FRAP activity assay with value of 40.21 � 2.19 mg TE/g extract. Total antioxidant capacity (1.23 � 0.033 mmol TE/g extract) was also found higher for CAÀ C, while CAÀ H activity was also comparable, however, CAÀ H showed higher metal chelating activity (22.74 � 0.001 mg EDTAE/g extract) than that of CAÀ C (17.55 � 0.22 mg EDTAE/g extract). These activities clearly revealed a direct relation between antioxidant potential and phenolic contents of CAÀ H and CAÀ C. In AChE and BChE inhibitory assay, CAÀ H and CAÀ E showed better inhibition (AChE: 8.24 � 0.77 & 4.46 � 0.007 mg GALAE/g extract; BChE: 5.40 � 0.02 & 1.92 � 0.24 mg GALAE/g extract) as compared to other fractions, whereas, against tyrosinase, CAÀ B was most active (37.35 � 0.53 mg KAE/g extract). CAÀ H and CAÀ C also showed higher inhibitory potential (0.98 � 0.08 & 0.58 � 0.01 mmol ACAE/g extract) against α-Amylase; while against α-Glucosidase, CAÀ E was the most active fraction. UHPLC/MS analysis of the methanolic extract of C. arvensis disclosed the presence of 62 compounds as sterols, triterpenes, flavonoids, fatty acids, alkaloids and coumarins. In Multivariate Analysis, the total phenolic contents were correlated strongly with all antioxidant assays except FRAP and DPPH. Regarding enzyme inhibitory properties,

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Section: Resultssupporting

confidence: 92%

Section: Discussionsupporting

confidence: 88%

Section: Discussionmentioning

confidence: 87%

Section: Multivariate Analysismentioning

confidence: 99%

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Total Bioactive Contents, Metabolic Profiling, Docking Studies, Antioxidant and Enzyme Inhibition Activities of Convolvulus Arvensis L. and Multivariate Analysis to Unravel a Potential Herb as Natural Resource for Pharmaceutical Industry

Tousif

Nazir

Saleem

et al. 2022

Chemistry & Biodiversity

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“…The main reason for the change in color of essential oil samples could be the alteration of the existing compounds in the EOs among the evaluated populations. Color changes in EO samples collected from various populations have been reported in previous report 18 . The EO content varied among populations, ranging from 0.40 to 0.78 (V/W) with the lowest and highest amounts was obtained in populations P5 and P8, respectively (Fig.…”

Section: Morphological Dimension Analysissupporting

confidence: 59%

Essential oil composition, morphological characterization, phenolic content and antioxidant activity of Iranian populations of Hymenocrater longiflorus Benth. (Lamiaceae)

Fattahpour,

Fattahi,

Hassani

2024

Sci Rep

Self Cite

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The study focused on the morphological and chemical characteristics of 200 Hymenocrater longiflorus Benth. genotypes found in natural habitats of eight regions in west of Iran. The primary objective of the study was to assess the morphological and phytochemical variability within populations grown in their natural habitats, with the aim of identifying their potential for domestication and utilization in pre-breeding programs. The plant height (PH) ranged from 50.32 to 69.65 cm, with the highest observed in population P8. The internode distances ranged from 4.7 to 6.47 cm, with the maximum distance found in P4. Flower lengths varied from 1.95 to 2.45 cm, with the minimum and maximum values observed in P4 and P3, respectively. The highest leaf length (5.20 cm) and width (3.87 cm) were recorded in P2. The aerial parts of the plant were utilized to extraction and determine the essential oil (EO) content and composition, which ranged from 0.40 to 0.78% (v/w). The analysis of EO by gas chromatography (GC) and gas chromatography mass spectrometry (GC/MS) identified 26 compounds, constituting 99–99.5% of the EOs. The main compounds in the EO and their percentage range (v/w DW) were tau-cadinol (0.62–55.56), mono (2-ethylhexyl) phthalate (8.10–94.70), elemol (0.21–19.11), β-spathulenol (0.08–14.39), 4-terpineol (0.23–10.19), and β-eudesmol (0.21–9.94). The main chemical groups found in EOs included oxygenated sesquiterpenes (1.12–68.43), and phthalates (9.73–94.72). Cluster analysis revealed three distinct chemotypes: chemotype I (populations 1 and 2) with major components of mono (2-ethylhexyl) phthalate, tau-cadinol, and α-elemol; chemotype II (population 5) rich in mono (2-ethylhexyl) phthalate; and chemotype III (populations 3, 4, 6–8) containing tau-cadinol, β-eudesmol, and 4-terpineol. The study also evaluated total phenolic, total flavonoid, and DPPH free radical scavenging activity in the fifty percent inhibitory concentration (IC50) in leaf and flower samples of the genotypes, along with estimating total anthocyanin content in the flower samples. The total phenolic content (TPC) in leaf and flower samples ranged from 7.89 to 107.18 mg GAE/g DW and 39.98 to 86.62 mg gallic acid equivalent (GAE)/g DW, respectively. Total flavonoid content (TFC) ranged from 81.04 to 143.46 mg QUE/g DW in leaf samples and from 94.82 to 133.26 mg quercetin equivalent (QUE)/g DW in flower samples. DPPHsc IC50 (µg/mL) ranged from 0.65 to 78.74 in leaf samples and from 4.38 to 7.71 in flower samples. Anthocyanin content ranged from 1.89 to 3.75 mg cyanidin-3-glucoside equivalent (C3GE)/g DW among populations. Canonical correspondence analysis and simple correlation demonstrated a strong association and correlations among the studied attributes. The negative correlations between leaf DPPH (DPPH L) IC50 and TFC (− 0.73), TPC (− 0.63), Elemol (− 0.90), and EO (− 0.85) indicate that these compounds have a significant impact on the antioxidant activity of the leaves. Furthermore, Fruit DPPH (DPPH F) IC50 showed a negative correlation with TPC (− 0.79) and TFC (− 0.78), but a positive correlation with flower anthocyanins (0.51), (Z)-β-Farnesene (0.66), and 4-Terpineol (0.57). Circular cluster analysis categorized the genotypes of all individuals in the eight studied populations into three main categories based on all the studied traits, indicating significant variation in phytochemical and morphological traits among populations, surpassing the within-populations variation.

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Peroxyl Radical Trapping Antioxidant Activity of Essential Oils and Their Phenolic Components

Pan,

Velasco Abadia,

Guo

et al. 2024

J. Agric. Food Chem.

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Essential oils (EOs) are gaining importance as sustainable food antioxidants, but kinetic data on peroxyl radical trapping are missing. Thirteen EOs from 11 botanical species were studied in the inhibited autoxidation of cumene by oxygen-uptake kinetics. EOs of Juniperus oxycedrus, Syzygium aromaticum, Thymus vulgaris, Thymbra capitata, Betula alba, Pimenta racemosa, and Satureja montana, containing 23−86% phenolic components by gas chromatography/mass spectrometry (GC−MS) analysis, afforded inhibition rate constants k inh in the order of 10 4 M −1 s −1 at 30 °C similar to reference butylhydroxytoluene (2,6-di-tert-butyl-4-methylphenol) (BHT). They matched or outperformed BHT in the protection of olive oil. The EOs Daucus carota and Cedrus atlantica with <1% phenols and those of Apium graveolens and Tagetes minuta with no phenolics had no chain-breaking activity. Key components carvacrol, thymol, eugenol, dihydroeugenol, umbelliferone, conyferyl alcohol,2,2, and phenol had k inh in the range of 10 3 −10 4 M −1 s −1 and, along with EOs containing them, could potentially replace BHT in the protection of food products.

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Phenolic contents, composition and antioxidant activity of essential oils obtained from Iranian populations of Apium graveolens, and their canonical correlation with environmental factors

Cited by 5 publications

References 22 publications

Total Bioactive Contents, Metabolic Profiling, Docking Studies, Antioxidant and Enzyme Inhibition Activities of Convolvulus Arvensis L. and Multivariate Analysis to Unravel a Potential Herb as Natural Resource for Pharmaceutical Industry

Total Bioactive Contents, Metabolic Profiling, Docking Studies, Antioxidant and Enzyme Inhibition Activities of Convolvulus Arvensis L. and Multivariate Analysis to Unravel a Potential Herb as Natural Resource for Pharmaceutical Industry

Essential oil composition, morphological characterization, phenolic content and antioxidant activity of Iranian populations of Hymenocrater longiflorus Benth. (Lamiaceae)

Peroxyl Radical Trapping Antioxidant Activity of Essential Oils and Their Phenolic Components

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