Phenolic Diversity and Antioxidant Activity of Artemisia abrotanum L. and Artemisia absinthium L. during Vegetation Stages

Abstract

Over the past ten years, particular attention has been paid to Artemisia L. genus plants and their chemical composition. Artemisia abrotanum L. and Artemisia absinthium L., which are traditional medicinal, aromatic plants with a strong digestive activity that is determined by the various phytochemicals. The research aim was to determine the variation in polyphenols in the samples of different vegetation stages of two Artemisia species and to evaluate the antioxidant activity of methanolic extracts in vitro. Phytochemical analysis of the Artemisia samples was carried out using spectrophotometric methods and HPLC-PDA techniques, while antioxidant activity was determined using DPPH, ABTS, FRAP, and CUPRAC assays. Significant differences in the diversity of phenolic compounds were found among Artemisia species during vegetation stages. Chlorogenic acid, 3,5-dicaffeoylquinic acid, and rutin were predominant among the phenolic compounds. The study provides valuable insights into the composition of phenolic compounds and flavonoids in Artemisia plants at different growth stages, shedding light on their potential pharmacological effects and antioxidant activities. These findings contribute to the knowledge of the quality and safety of herbal materials derived from Artemisia species.

In Vitro and In Silico Anti-Glioblastoma Activity of Hydroalcoholic Extracts of Artemisia annua L. and Artemisia vulgaris L.

“…Considering that numerous studies have demonstrated significant differences in the chemical composition and biological effects of Artemisia spp. based on the geographical origin of the plants, the specific plant part used for extraction, and the extraction method itself [ 11 , 29 , 30 ], our findings that chlorogenic acid is a prevalent phenolic compound in A. annua and A. vulgaris are consistent with other data from the same geographical region [ 31 , 32 ].…”

Phenolic Compounds of Six Unexplored Asteraceae Species from Asia: Comparison of Wild and Cultivated Plants

“…In Most compounds identified in A. jacutica are commonly encountered in the genus, including caffeoyl quinic acids (prevalent in various wormwoods [51]), quercetin and isorhamnetin glycosides [61], and flavonoid aglycones [62]. However, some metabolites are rare in the Artemisia genus, such as caffeoyl glucaric acids (previously reported only in A. annua [63] and A. absinthium [64]) and p-coumaroyl spermines (detected in A. caruifolia [65]).…”