Phenolic Glycoside Isolated from Seeds of the Greater Plantain (Plantago major L.)

Profiling of antioxidant potential and phytoconstituents of Plantago coronopus

“…Verbascoside was the main phenolic identified in all organs corresponding to 95%, 78% and 85% of the total phenolics in roots, leaves and flowers, respectively. Roots had the highest content of verbascoside, followed by leaves and flowers, which might be explained by the allelopathic properties of that compound on soil phytopathogenic fungi, inhibiting their growth (Egorov et al, 2004). Described as a main compound in plantains, verbascoside levels in this study were higher than those reported by other authors for the aerial parts of P. coronopus and five other Plantago species (Janković et al, 2012).…”

“…Described as a main compound in plantains, verbascoside levels in this study were higher than those reported by other authors for the aerial parts of P. coronopus and five other Plantago species (Janković et al, 2012). This major component has known antioxidant, anti-inflammatory, and antifungal properties, along with cytotoxic activity (Egorov et al, 2004;Gálvez et al, 2005;Ksouri et al, 2012).…”

Effectiveness of different methods for the extraction of principle actives and phytochemicals content in medicinal herbals

“…Additionally, few signals were detected from anomeric hydrogens, which suggested the presence of a mixture of sugars and oxygenated aliphatic compounds such as tartaric acid, citric acid, malic acid, malonic acid, and succinic acid, which have been previously reported in this species (Olennikov et al, 2005). The phenolic heterosides detected in this study suggests the presence of flavonoids such as glycosylated flavanone (Endo et al, 1981), the flavones luteolin 7-glucoside and luteolin 7glucuronide (Lebedev-Kosov, 1976), or glycosylated phenolic acids such as verbascoside, which have been previously isolated from this species (Egorov et al, 2004). Therefore, the detection of a few signals in the aliphatic region can in principle be attributed to the presence of terpenes and steroids, further suggesting the presence of fatty acids such as stearic acid, pentadecanoic acid, oleic acid, eicosapentaenoic acid, and docosahexaenoic acid, which are commonly found in this species (Ringbom et al, 2001).…”

“…Other bioactive aromatic compounds such as arctiin (Coulerie et al, 2016), free sugars or heterosides such as the glycosylated phenolics arctiisesquineolignan B and arctiiphenolglycoside A (He et al, 2016), glycosylated lactones (Yang et al, 2015), butyrolactone lignans (Chagas-Paula et al, 2015), terpenes, steroids and fatty acids such as the amide-derived fatty acids (Yang et al, 2016) have been reported. In PM has widely been reported flavonoids and phenolic acids derived from hydroxycinnamic, chlorogenic and neochlorogenic acids (Maksyutina, 1971a;Maksyutina, 1971b), aliphatic acids (e.g., such as tartaric acid, citric acid, malic acid, malonic acid and succinic acid) (Olennikov et al, 2005), flavonoids such as glycosylated flavanone (Endo et al, 1981) and flavones luteolin 7-glucoside and luteolin 7glucuronide (Lebedev, 1976), glycosylated phenolic acids such as verbascoside (Egorov et al, 2004), terpenes and steroids, fatty acids such as stearic acid, pentadecanoic acid, oleic acid, eicosapentaenoic acid and docosahexaenoic acid (Ringbom et al, 2001).…”

Renoprotective Effect of Plantago major Against Proteinuria and Apoptosis Induced by Adriamycin in Rat

“…The exact mechanism for this hypolipidemic action of P. major extract in our study is not clear, but it might be contributed to its protection against proteinuria and subsequent hyperalbuminemia, which could minimize the compensatory production of cholesterol by the liver. However, other mechanisms including suppressing fatty acid synthesis, accelerating fatty acid β -oxidation, and stimulating cholesterol catabolism mainly by phenylpropanoid glycosides might be involved [ 22 , 23 ].…”