Phenomenological simulation of self-organization of microtubule driven by dynein c

Abstract

It was recently noticed that in vitro motility assays, driven by random distributed dynein c, microtubules could form self-organized circular patterns, which could be of importance to the design of nanobiomechanical machines. In order to determine key parameters that control the self-organized movement of microtubules, a phenomenological modeling study taking account of the microtubule joining probability distribution and microtubule bias was conducted to investigate the self-organization of microtubules driven by dynein motors.

Patterns of molecular motors that guide and sort filaments

“…Such interactions however can lead to very interesting phenomena, [35][36][37] and it will be worthwhile to consider them in the Fig. 4 A concept sorter.…”

“…Interactions between filaments were neglected because they normally do not occur in standard gliding assays. Such interactions however can lead to very interesting phenomena, [35][36][37] and it will be worthwhile to consider them in the Fig. 4 A concept sorter.…”